Search Back New search Go to resultsDiseaseMain groupHematological Diseases, Non-MalignantProtocol groupAnemias, CytopeniasHemolytic DiseasesDiseaseAnemia, Autoimmune Hemolytic AnemiaSubgroupCold Agglutinin Diseasewarm typeICD10D59.1MeSHAnemia, Hemolytic, AutoimmuneSequenceCADENZA : SUTI6.5, Autoimmune Hemolytic Anemia, Cold Agglutinin Disease, C1 (PID2248) -|- SUTI6.5, C2+ (PID2249)ChemotherapyChemo-substanceAzathioprineBendamustineBortezomibCiclosporin ACyclophosphamideFludarabineMycophenolate mofetilPrednisoloneRituximabChemo-substanceAzathioprineBendamustineBortezomibCiclosporin ACyclophosphamideFludarabineMycophenolate mofetilPrednisoloneRituximabChemo-substanceAzathioprineBendamustineBortezomibCiclosporin ACyclophosphamideFludarabineMycophenolate mofetilPrednisoloneRituximabChemo-substanceAzathioprineBendamustineBortezomibCiclosporin ACyclophosphamideFludarabineMycophenolate mofetilPrednisoloneRituximabNo. Substances12 RadiotherapySupportive therapySupportive substanceAciclovirBalanced Crystalloid SolutionCalcium carbonateColecalciferolCotrimoxazoleDexamethasoneDimetindenEnoxaparinFolic acidFosaprepitantGranisetronMesnaPantoprazoleParacetamolPegfilgrastimPrednisoloneSutimlimabSupportive substanceAciclovirBalanced Crystalloid SolutionCalcium carbonateColecalciferolCotrimoxazoleDexamethasoneDimetindenEnoxaparinFolic acidFosaprepitantGranisetronMesnaPantoprazoleParacetamolPegfilgrastimPrednisoloneSutimlimabSupportive substanceAciclovirBalanced Crystalloid SolutionCalcium carbonateColecalciferolCotrimoxazoleDexamethasoneDimetindenEnoxaparinFolic acidFosaprepitantGranisetronMesnaPantoprazoleParacetamolPegfilgrastimPrednisoloneSutimlimabSupportive substanceAciclovirBalanced Crystalloid SolutionCalcium carbonateColecalciferolCotrimoxazoleDexamethasoneDimetindenEnoxaparinFolic acidFosaprepitantGranisetronMesnaPantoprazoleParacetamolPegfilgrastimPrednisoloneSutimlimabNo. Substances1256810Protocol classificationTherapy classificationalternativecurrent standardIntensityStandard doseTherapy indicationFirst lineRefractory diseaseSecond lineseveral possibleThird line Therapy phaseTherapy intentiondisease controlRisksAnemia Hb below 8g/dlArthalgiaCardiotoxicityDiarrheaDyspneaEmetogenicityEmetogenicity (MASCC/ESMO)Febrile NeutropeniaHeadacheHerpes ZosterHyperbilirubinemiaHyperglycemiaHypertensionHypotensionIncrease AminotransferasesInfectionsLeukopeniaMyalgiasNasopharyngitisNeutropeniaParesthesiaPneumoniaPyrexiaRashRenal failure!Thrombocytopenia below 50 000/µlThromboembolic Event only studiesPublicationAuthorBerentsen SBirgens HEmilia GHoward JJäger UMichel MMoyo VMRossi GRöth ADiseaseautoimmunhämolytische Anämie, kälteagglutinin-induzierte Durchblutungsstörungenautoimmunhämolytische Anämie, Kälteagglutininerkrankungautoimmunhämolytische Anämie, KälteagglutininkrankheitAutoimmunhämolytische Anämie, Kälteagglutininkrankheit, symptomatisch, Hämoglobinwert unter 10.0 g/dL, autoimmunhämolytische Anämie, vom Wärmetyp, Drittlinieautoimmunhämolytische Anämie, vom Wärmetyp, refraktäre Erkrankungprimäre autoimmunhämolytische Anämie, vom Wärmetypprimäre autoimmunhämolytische Anämie, vom Wärmetyp, ErstlinieOriginDepartment of Haematology, Copenhagen University Hospital, Herlev Department of Hematology, ASST Spedali Civili, Brescia, Italy, GIMEMA studyDepartment of Medicine, Haugesund Hospital, Haugesund, NorwayDepartment of Research and Innovation, Haugesund Hospital, Hausgesund, NorwayDipartimento di Scienze Mediche, Oncologiche e Radiologiche, Università di Modena, ItalyHaugesund Hospital, Haugesund, NorwayJamaica Hospital Medical Center, Jamaica, USARoyal Free Hospital and University College Medical School, UKSidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, USAUniversite Paris-Est Creteil, France, the RAIHA studyWest German Cancer Center, University Hospital Essen, University of Duisburg-Essen, Essen, German, CADENZA trialProtocols in Revision 13 protocols foundProtocols under revision.Azathioprine 2, Autoimmune Hemolytic Anemia, warm type (PID2008)Bortezomib 1,3, Autoimmune Hemolytic Anemia, Cold Agglutinin Disease (PID2023)Cyclophosphamide 50, Autoimmune Hemolytic Anemia, warm type (PID2016)Mycophenolate Mofetil (500/1000), Autoimmune Hemolytic Anemia, warm type (PID2014)Prednisolone (1.5/0.75/0.5) / Rituximab 375, Autoimmune Hemolytic Anemia, warm type (PID2007)Prednisolone (1.5/0.75/0.5), Autoimmune Hemolytic Anemia, warm type (PID2006)Prednisolone 1 / Rituximab 1000, Autoimmune Hemolytic Anemia, warm type (PID2015)Prednisolone 5 / Ciclosporin (2.5/1.5), Autoimmune Hemolytic Anemia, warm type (PID2013)Rituximab 375 / Bendamustine 90, Autoimmune Hemolytic Anemia / Cold Agglutinin Disease (PID1089)Rituximab 375 / Fludarabine 25, Autoimmune Hemolytic Anemia, Cold Agglutinin Disease (PID2022)Rituximab 375, Autoimmune Hemolytic Anemia, Cold Agglutinin Disease (PID2005)Sutimlimab 6.5, Autoimmune Hemolytic Anemia, Cold Agglutinin Disease, Cycle 1. (PID2248)Sutimlimab 6.5, Autoimmune Hemolytic Anemia, Cold Agglutinin Disease, Cycle 2+. (PID2249)