Search Back New search Go to resultsDiseaseMain groupCross-Sectional, Transplantation, Cellular TherapyPediatric Oncology and HematologyProtocol groupLeukemias (ped.)radiotherapyDiseaseAcute Lymphoblastic LeukaemiaMalignant MeningitisSubgroupB-ALLLeukemic MeningitisT-ALLICD10C79.3C91.0-MeSHMeningeal CarcinomatosisPrecursor B-Cell Lymphoblastic Leukemia-LymphomaSequenceChemotherapyChemo-substanceAmsacrineClofarabinCyclophosphamideCytarabineDaunorubicinDexamethasoneDoxorubicinEtoposideMercaptopurineMethotrexateMethylprednisolonePeg asparaginaseTioguaninVincristineChemo-substanceAmsacrineClofarabinCyclophosphamideCytarabineDaunorubicinDexamethasoneDoxorubicinEtoposideMercaptopurineMethotrexateMethylprednisolonePeg asparaginaseTioguaninVincristineChemo-substanceAmsacrineClofarabinCyclophosphamideCytarabineDaunorubicinDexamethasoneDoxorubicinEtoposideMercaptopurineMethotrexateMethylprednisolonePeg asparaginaseTioguaninVincristineChemo-substanceAmsacrineClofarabinCyclophosphamideCytarabineDaunorubicinDexamethasoneDoxorubicinEtoposideMercaptopurineMethotrexateMethylprednisolonePeg asparaginaseTioguaninVincristineNo. Substances12345678910 RadiotherapySupportive therapySupportive substanceAllopurinolBalanced Crystalloid SolutionCotrimoxazoleDextrose 5%FluorometholoneFolinic acidGranisetronMesnaMethylprednisoloneNaCl 0.9%Potassium chlorideSodium BicarbonateSupportive substanceAllopurinolBalanced Crystalloid SolutionCotrimoxazoleDextrose 5%FluorometholoneFolinic acidGranisetronMesnaMethylprednisoloneNaCl 0.9%Potassium chlorideSodium BicarbonateSupportive substanceAllopurinolBalanced Crystalloid SolutionCotrimoxazoleDextrose 5%FluorometholoneFolinic acidGranisetronMesnaMethylprednisoloneNaCl 0.9%Potassium chlorideSodium BicarbonateSupportive substanceAllopurinolBalanced Crystalloid SolutionCotrimoxazoleDextrose 5%FluorometholoneFolinic acidGranisetronMesnaMethylprednisoloneNaCl 0.9%Potassium chlorideSodium BicarbonateNo. Substances1234791011Protocol classificationTherapy classificationstudy analogStudy protocol, currentIntensityhigh doseStandard doseTherapy indicationFirst lineTherapy phaseConsolidationInductionMaintenancePre-phaseReinductionTherapy intentioncurativeRisksEmetogenicityEmetogenicity (MASCC/ESMO) only studiesPublicationAuthorHorstmann MDiseaseVorläufer-B- und T-Zell Leukämie, Hochrisiko ALLOriginGesellschaft für Pädiatrische Onkologie und Hämatologie, Studienprotokoll COALL 08-09Protocols in Revision 22 protocols foundProtocols under revision.PAED COALL 08-09, maintenance, B-ALL/T-ALL, LR-reduced, and HR-reduced (PID24 V1.0)PAED COALL 08-09, Maintenance, B-ALL/T-ALL, LR-Standard and LR-Intensified and HR-Standard and HR- Intensified (PID25 V1.0)PAED COALL 08-09, maintenance, B-ALL/T-ALL, MTX intrathecal (without CNS irradiation) (PID33 V1.0)PAED COALL 08-09, induction, all patients (PID11 V1.0)PAED COALL 08-09, Intensive phase, B-ALL, HR-Intensified C1a-C4-C4-C3-C3-C1a-C5 (PID19 V1.0)PAED COALL 08-09, intensive phase, B-ALL, HR-Intensified C1b-C4-C3-C3-C1a-C5 (PID20 V1.0)PAED COALL 08-09, intensive phase, B-ALL, LR intensified and HR reduced, and HR standard C1a-C4-C4-C3-C3-C1a (PID15 V1.0)PAED COALL 08-09, intensive phase, B-ALL, LR intensified and HR standard C1b-C4-C4-C3-C3-C1a (PID14 V1.0)PAED COALL 08-09, intensive phase, B-ALL, LR standard C1b-C2-C3-C2 (PID13 V1.0)PAED COALL 08-09, Intensive Phase, B-ALL, LR Standard and LR Reduced C1a-C2-C3-C2. (PID12 V1.0)PAED COALL 08-09, intensive phase, T-ALL, HR-Intensified C4-C1a-C4-C3-C3-C1a-C5 (PID18 V1.0)PAED COALL 08-09, intensive phase, T-ALL, HR standard C4-C1b-C4-C3-C1a (PID17 V1.0)PAED COALL 08-09, intensive phase, T-ALL, HR standard and HR reduced C4-C1a-C4-C3-C3-C1a (PID16 V1.0)PAED COALL 08-09, Reinduction, B-ALL, LR-Standard R2(ADR)-R3 (PID30 V1.0)PAED COALL 08-09, Reinduction, B-ALL, LR-Standard R2(DNR)-R3 (PID22 V1.0)PAED COALL 08-09, Reinduction, B-ALL/T-ALL, HR Intensified R2 before CNS (PID32 V1.0)PAED COALL 08-09, Reinduction, B-ALL/T-ALL, LR-Intensified and HR-Standard and HR-Intensified R2(ADR)-R2-R3-R3 (PID31 V1.0)PAED COALL 08-09, Reinduction, B-ALL/T-ALL, LR-Intensified and HR-Standard and HR-Intensified R2(DNR)-R2-R3-R3 (PID23 V1.0)PAED COALL 08-09, Reinduction, B-ALL/T-ALL, LR-Reduced and HR-Reduced R1 (PID21 V1.0)PAED COALL 08-09, Pre-phase, all patients (PID10 V1.0)PAED COALL 08-09, CNS, B-ALL/T-ALL, initial CNS involvement (PID29 V1.0)PAED COALL 08-09, CNS, B-ALL/T-ALL, LR and HR (B-ALL leukoc. up to 200000/µl, T-ALL leukoc. up to 100000/µl) (PID28 V1.0)
