Search Protocols under revision. Back New search Go to resultsDiseaseMain groupHematologic NeoplasmsProtocol groupAcute LeukemiasAggressive LymphomasT-Cell and NK-Cell NeoplasmsDiseaseAcute Lymphoblastic LeukaemiaNHL, B-Cell Type, Anaplastic Large Cell Lymphoma, ALK-PositiveNHL, B-Cell Type, Burkitt's LymphomaNHL, B-Cell Type, Lymphoblastic LymphomaNHL, T-Cell Type, Adult T-Cell Leukemia or LymphomaNHL, T-Cell Type, Lymphoblastic LymphomaSubgroupB-ALLBCR-ABL positivePh/BCR-ABL-T-ALLICD10C83.5C83.7C84.6C91.0-C91.5-MeSHPrecursor B-Cell Lymphoblastic Leukemia-LymphomaSequenceGMALL 08/2013-ALL/LBL, 56 - 75GMALL 08/2013-ALL/LBL, 56 - 75, Ph/BCR-ABL+GMALL 08/2013-ALL/LBL 18 - 55GMALL 08/2013-B-ALL/NHL 2002 Regimen, 18 - 55GMALL 08/2013-B-ALL/NHL 2002 regimen, older than 55, B-ALL onlyGMALL 08/2013-B-ALL/NHL 2002 regimen, older than 55, NHL onlyT-ALL: Hyper-CVAD (CYCL300/VNCR2/DOXO50/DEXA40)/RITU375, ALL/NHL, C1 (PID2061) -|- C2 (PID2064) -|- C3 (PID2061) -|- C4 (PID2064) -|- C4N (PID2083) -|- C5 (PID2063) -|- C5N (PID2083) -|- C6 (PID2065) -|- C7 (PID2063) -|- C8 (PID2065) -|- Month 1-5 (PID2072) -|- Month 6 (PID2083) -|- Month 7 (PID2083) -|- Month 8-17 (PID2072) -|- Month 18 (PID2074) -|- Month 19 (PID2061) -|- Month 20-30 (PID2072)ChemotherapyChemo-substanceCyclophosphamideCytarabineDaunorubicinDexamethasoneDoxorubicinEtoposideIdarubicinMercaptopurineMethotrexateNelarabinePeg asparaginasePonatinibPrednisoloneRituximabVincristineVindesineChemo-substanceCyclophosphamideCytarabineDaunorubicinDexamethasoneDoxorubicinEtoposideIdarubicinMercaptopurineMethotrexateNelarabinePeg asparaginasePonatinibPrednisoloneRituximabVincristineVindesineChemo-substanceCyclophosphamideCytarabineDaunorubicinDexamethasoneDoxorubicinEtoposideIdarubicinMercaptopurineMethotrexateNelarabinePeg asparaginasePonatinibPrednisoloneRituximabVincristineVindesineChemo-substanceCyclophosphamideCytarabineDaunorubicinDexamethasoneDoxorubicinEtoposideIdarubicinMercaptopurineMethotrexateNelarabinePeg asparaginasePonatinibPrednisoloneRituximabVincristineVindesineNo. Substances12345678 RadiotherapySupportive therapySupportive substanceAciclovirAmphotericin BBalanced Crystalloid SolutionCiprofloxacinCotrimoxazoleDexamethasoneDextrose 5%DimetindenFamotidineFilgrastimFolinic acidFurosemideGranisetronMesnaNaCl 0.9%ParacetamolPegfilgrastimPotassium chloridePrednisoloneSodium BicarbonateSupportive substanceAciclovirAmphotericin BBalanced Crystalloid SolutionCiprofloxacinCotrimoxazoleDexamethasoneDextrose 5%DimetindenFamotidineFilgrastimFolinic acidFurosemideGranisetronMesnaNaCl 0.9%ParacetamolPegfilgrastimPotassium chloridePrednisoloneSodium BicarbonateSupportive substanceAciclovirAmphotericin BBalanced Crystalloid SolutionCiprofloxacinCotrimoxazoleDexamethasoneDextrose 5%DimetindenFamotidineFilgrastimFolinic acidFurosemideGranisetronMesnaNaCl 0.9%ParacetamolPegfilgrastimPotassium chloridePrednisoloneSodium BicarbonateSupportive substanceAciclovirAmphotericin BBalanced Crystalloid SolutionCiprofloxacinCotrimoxazoleDexamethasoneDextrose 5%DimetindenFamotidineFilgrastimFolinic acidFurosemideGranisetronMesnaNaCl 0.9%ParacetamolPegfilgrastimPotassium chloridePrednisoloneSodium BicarbonateNo. Substances145678910111516Protocol classificationTherapy classificationcurrent standardStudy protocol, currentIntensityhigh doseStandard doseTherapy indicationFirst lineRelapse therapyTherapy phaseConsolidationInductionMaintenancePre-phaseReinductionTherapy intentioncurativecurative or palliativeRisksAnemia Hb below 8g/dlAstheniaDiarrheaEmetogenicityEmetogenicity (ASCO)Emetogenicity (MASCC/ESMO)Febrile NeutropeniaHypertensionIncrease AminotransferasesInfectionsMyalgiasNeuropathyNeutropeniaSeizuresThrombocytopenia below 50 000/µl only studiesPublicationAuthorDeAngelo DJGökbuget DGökbuget NHoelzer DRausch CRDiseaseAkute lymphatische Leukämie, 18-55 JahreAkute lymphatische Leukämie, lymphoblastische Lymphome, 18-55 JahreAkute lymphatische Leukämie, lymphoblastische Lymphome, 56-75 JahreAkute lymphatische Leukämie, lymphoblastische Lymphome, Therapieversagen oder MRD-Persistenz nach Konsolidation I,18-55 JahreAkute lymphatische Leukämie, Ph/BCR-ABL+, 18-65 Jahre, ECOG 0-2Hochmaligne B-ALL/T-ALL und Burkitt-Lymphom bei Erwachsenen, ErstlinieHochmaligne B-ALL und B-NHL bei Erwachsenen, ErstlinieT-ALL/LBL, therapierefraktär oder rezidiviertOriginDepartment of Medical Oncology, Dana-Farber Cancer Institute, Boston, Cancer and Leukemia Group B study 19801Division of Pharmacy, University of Texas MD Anderson Cancer Center, Houston, TexasGerman Multicenter Study Group for Adult Acute Lymphoblastic LeukemiaGerman Multicenter Study Group for Adult Acute Lymphoblastic Leukemia, GMALL-EVOLVE 02/2024German Multicenter Study Group for Adult Acute Lymphoblastic Leukemia, GMALL 07/2017Protocols in Revision 21 protocols foundGMALL 08/2013 - ALL maintenance, 18 - 55 years old (PID638 V2.1)GMALL 08/2013 - ALL/LBL Consolidation IV (Week 30), 56 - 75 years (PID1097 V1.0)GMALL 08/2013 - ALL/LBL Induction I (Day 6), 18 - 55 years, all risk groups (PID592 V2.0)GMALL 08/2013 - ALL/LBL consolidation I (day 60), 18 - 55 years, all risk groups (PID595 V3.0)GMALL 08/2013 - ALL/LBL Consolidation I (Week 9), 56 - 75 years (PID1086 V1.0)GMALL 08/2013 - ALL/LBL Consolidation II (Week 14), 18 - 55 years (PID1098 V1.0)GMALL 08/2013 - ALL/LBL Consolidation II (Week 15), 56 - 75 years (PID1091 V1.1)GMALL 08/2013 - ALL/LBL consolidation II in treatment failure/MRD persistence of T-ALL/T-LBL, 18 - 55 years (PID965 V2.0)GMALL 08/2013 - ALL/LBL consolidation III and V (week 24,34), 56 - 75 yrs (PID1090 V1.1)GMALL 08/2013 - ALL/LBL Reinduction (Week 19), 18 - 55 years (PID636 V2.1)GMALL 08/2013 - ALL/LBL Reinduction (Week 19), 56 - 75 years (PID1096 V1.1)GMALL 08/2013 - ALL/LBL Pre-phase, 18 - 55 yrs (PID591 V2.0)GMALL 08/2013 - ALL/LBL Pre-phase, 56 - 75 yrs (PID1085 V1.0)GMALL 08/2013 - B-ALL/NHL 2002 regimen, Rituximab consolidation (PID784 V1.0)GMALL 08/2013-ALL/LBL - ALL Induction II (day 23), 18 - 55 years, all risk groups (PID594 V2.0)GMALL 08/2013-ALL/LBL Consolidation III and V (week 24, 32), 18 - 55 years old (PID634 V2.0)GMALL 08/2013-ALL/LBL Consolidation IV and VI (week 27, 35), 18 - 55 years old (PID632 V2.1)GMALL-EVOLVE- ALL Consolidation II (week 19 Ponatinib), 18 - 65 years, Ph/BCR-ABL+ (PID3127 V1.0)GMALL-EVOLVE- ALL reinduction (week 24 Ponatinib), 18 - 65 years, Ph/BCR-ABL+ (PID3129 V1.0)Nelarabine 1500, T-ALL/T-LBL (PID1922 V1.0)Nelarabine 650 / Peg-asparaginase 1500, T-ALL, maintenance, month 6, 7 (PID2083 V1.1)
