Search Back New search Go to resultsDiseaseMain groupSolid TumorsProtocol groupGynecological OncologySarcomasDiseaseSoft Tissue SarcomaSubgroupLeiomyosarcomaLeiomyosarcoma, uterineICD10C49.-MeSHLeiomyosarcomaNeoplasms, Connective and Soft TissueSarcomaUterine NeoplasmsSequenceGEMC900/DOCE75, Soft Tissue Sarcoma, adj., A (PID1945) -|- DOXO60, B (PID1946)LMS-04: DOXO60/TRAB1.1, Soft Tissue Sarcoma (PID2210) -|- TRAB1.1, Maint. (PID2219)ChemotherapyChemo-substanceDocetaxelDoxorubicinGemcitabineTrabectedinChemo-substanceDocetaxelDoxorubicinGemcitabineTrabectedinChemo-substanceDocetaxelDoxorubicinGemcitabineTrabectedinChemo-substanceDocetaxelDoxorubicinGemcitabineTrabectedinNo. Substances12 RadiotherapySupportive therapySupportive substanceBalanced Crystalloid SolutionDexamethasoneGranisetronPegfilgrastimSupportive substanceBalanced Crystalloid SolutionDexamethasoneGranisetronPegfilgrastimSupportive substanceBalanced Crystalloid SolutionDexamethasoneGranisetronPegfilgrastimSupportive substanceBalanced Crystalloid SolutionDexamethasoneGranisetronPegfilgrastimNo. Substances34Protocol classificationTherapy classificationalternativeIntensityStandard doseTherapy indicationFirst lineTherapy phaseTherapy intentioncurativepalliativeRisksAllergic ReactionAnemia Hb below 8g/dlCardiotoxicityConstipationDiarrheaEdemaEmetogenicity (MASCC/ESMO)Febrile NeutropeniaHyperbilirubinemiaIncrease AminotransferasesIncrease Creatinine PhosphokinaseInfectionsMucositisNeuropathyNeutropeniaPyrexiaThrombocytopenia below 50 000/µl only studiesPublicationAuthorHensley MLPautier PDiseasehigh-grade uterines Leiomyosarkom, FIGO I-IIIA, ECOG 0-1, adjuvantLeiomyosarkom, metastasiert oder lokal fortgeschritten, inoperabel, ErstlinieOriginInstitut Gustave-Roussy, Villejuif, France, LMS-04 trialMemorial Sloan-Kettering Cancer Center, New York, SARC 005 trialProtocols in Revision 4 protocols foundProtocols under revision.Doxorubicin 60 / Trabectedin 1.1, Soft Tissue Sarcoma (PID2210 V1.0)Doxorubicin 60, Soft Tissue Sarcoma, adjuvant, Part B (PID1946 V1.0)Gemcitabine 900 / Docetaxel 75, Soft Tissue Sarcoma, adjuvant, part A (PID1945 V1.0)Trabectedin 1.1, Soft Tissue Sarcoma, maintenance (PID2219 V1.0)
