Search Back New search Go to resultsDiseaseMain groupHematologic NeoplasmsProtocol groupAcute LeukemiasAggressive LymphomasT-Cell and NK-Cell NeoplasmsDiseaseAcute Lymphoblastic LeukaemiaNHL, B-Cell Type, Anaplastic Large Cell Lymphoma, ALK-PositiveNHL, B-Cell Type, Burkitt's LymphomaNHL, B-Cell Type, Lymphoblastic LymphomaNHL, T-Cell Type, Adult T-Cell Leukemia or LymphomaNHL, T-Cell Type, Lymphoblastic LymphomaSubgroupB-ALLPh/BCR-ABL+Ph/BCR-ABL-T-ALLICD10C83.5C83.7C84.6C91.0-C91.5-MeSHPrecursor B-Cell Lymphoblastic Leukemia-LymphomaPrecursor Cell Lymphoblastic Leukemia-LymphomaSequenceGMALL 08/2013-ALL/LBL, 56 - 75GMALL 08/2013-ALL/LBL, 56 - 75, Ph/BCR-ABL+GMALL 08/2013-ALL/LBL 18 - 55GMALL 08/2013-ALL/LBL 18 - 55, Ph/BCR-ABL+GMALL 08/2013-B-ALL/NHL 2002 Regimen, 18 - 55GMALL 08/2013-B-ALL/NHL 2002 regimen, older than 55, B-ALL onlyGMALL 08/2013-B-ALL/NHL 2002 regimen, older than 55, NHL onlyT-ALL: Hyper-CVAD (CYCL300/VNCR2/DOXO50/DEXA40)/RITU375, ALL/NHL, C1 (PID2061) -|- C2 (PID2064) -|- C3 (PID2061) -|- C4 (PID2064) -|- C4N (PID2083) -|- C5 (PID2063) -|- C5N (PID2083) -|- C6 (PID2065) -|- C7 (PID2063) -|- C8 (PID2065) -|- Month 1-5 (PID2072) -|- Month 6 (PID2083) -|- Month 7 (PID2083) -|- Month 8-17 (PID2072) -|- Month 18 (PID2074) -|- Month 19 (PID2061) -|- Month 20-30 (PID2072)ChemotherapyChemo-substanceCyclophosphamideCytarabineDaunorubicinDexamethasoneDoxorubicinEtoposideIdarubicinMercaptopurineMethotrexateNelarabinePeg asparaginasePrednisoloneRituximabVincristineVindesineChemo-substanceCyclophosphamideCytarabineDaunorubicinDexamethasoneDoxorubicinEtoposideIdarubicinMercaptopurineMethotrexateNelarabinePeg asparaginasePrednisoloneRituximabVincristineVindesineChemo-substanceCyclophosphamideCytarabineDaunorubicinDexamethasoneDoxorubicinEtoposideIdarubicinMercaptopurineMethotrexateNelarabinePeg asparaginasePrednisoloneRituximabVincristineVindesineChemo-substanceCyclophosphamideCytarabineDaunorubicinDexamethasoneDoxorubicinEtoposideIdarubicinMercaptopurineMethotrexateNelarabinePeg asparaginasePrednisoloneRituximabVincristineVindesineNo. Substances12345678 RadiotherapySupportive therapySupportive substanceAmphotericin BBalanced Crystalloid SolutionCiprofloxacinCotrimoxazoleDexamethasoneDextrose 5%DimetindenFamotidineFilgrastimFolinic acidFurosemideGranisetronMesnaNaCl 0.9%ParacetamolPegfilgrastimPotassium chloridePrednisoloneSodium BicarbonateSupportive substanceAmphotericin BBalanced Crystalloid SolutionCiprofloxacinCotrimoxazoleDexamethasoneDextrose 5%DimetindenFamotidineFilgrastimFolinic acidFurosemideGranisetronMesnaNaCl 0.9%ParacetamolPegfilgrastimPotassium chloridePrednisoloneSodium BicarbonateSupportive substanceAmphotericin BBalanced Crystalloid SolutionCiprofloxacinCotrimoxazoleDexamethasoneDextrose 5%DimetindenFamotidineFilgrastimFolinic acidFurosemideGranisetronMesnaNaCl 0.9%ParacetamolPegfilgrastimPotassium chloridePrednisoloneSodium BicarbonateSupportive substanceAmphotericin BBalanced Crystalloid SolutionCiprofloxacinCotrimoxazoleDexamethasoneDextrose 5%DimetindenFamotidineFilgrastimFolinic acidFurosemideGranisetronMesnaNaCl 0.9%ParacetamolPegfilgrastimPotassium chloridePrednisoloneSodium BicarbonateNo. Substances145689101116Protocol classificationTherapy classificationcurrent standardStudy protocol, currentIntensityhigh doseStandard doseTherapy indicationFirst lineRelapse therapyTherapy phaseConsolidationInductionMaintenancePre-phaseReinductionTherapy intentioncurativecurative or palliativeRisksAnemia Hb below 8g/dlAstheniaDiarrheaEmetogenicityEmetogenicity (MASCC/ESMO)Febrile NeutropeniaHypertensionIncrease AminotransferasesInfectionsMyalgiasNeuropathyNeutropeniaSeizuresThrombocytopenia below 50 000/µl only studiesPublicationAuthorDeAngelo DJGökbuget DGökbuget NHoelzer DRausch CRDiseaseAkute lymphatische Leukämie, 18-55 JahreAkute lymphatische Leukämie, lymphoblastische Lymphome, 18-55 JahreAkute lymphatische Leukämie, lymphoblastische Lymphome, 56-75 JahreAkute lymphatische Leukämie, lymphoblastische Lymphome, Therapieversagen oder MRD-Persistenz nach Konsolidation I,18-55 JahreHochmaligne B-ALL/T-ALL und Burkitt-Lymphom bei Erwachsenen, ErstlinieHochmaligne B-ALL und B-NHL bei Erwachsenen, ErstlinieT-ALL/LBL, therapierefraktär oder rezidiviertOriginDepartment of Medical Oncology, Dana-Farber Cancer Institute, Boston, Cancer and Leukemia Group B study 19801Division of Pharmacy, University of Texas MD Anderson Cancer Center, Houston, TexasGerman Multicenter Study Group for Adult Acute Lymphoblastic LeukemiaGerman Multicenter Study Group for Adult Acute Lymphoblastic Leukemia, GMALL 07/2017Protocols in Revision 19 protocols foundProtocols under revision.GMALL 08/2013 - ALL maintenance, 18 - 55 years old (PID638 V2.1)GMALL 08/2013 - ALL/LBL consolidation III and V (weeks 24, 32), 18 - 55 years (PID634 V2.0)GMALL 08/2013 - ALL/LBL Consolidation IV (Week 30), 56 - 75 years (PID1097 V1.0)GMALL 08/2013 - ALL/LBL Induction I (Day 6), 18 - 55 years, all risk groups (PID592 V2.0)GMALL 08/2013 - ALL/LBL Induction II (Day 23), 18 - 55 years, all risk groups (PID594 V2.0)GMALL 08/2013 - ALL/LBL consolidation I (day 60), 18 - 55 years, all risk groups (PID595 V3.0)GMALL 08/2013 - ALL/LBL Consolidation I (Week 9), 56 - 75 years (PID1086 V1.0)GMALL 08/2013 - ALL/LBL Consolidation II (Week 14), 18 - 55 years (PID1098 V1.0)GMALL 08/2013 - ALL/LBL Consolidation II (Week 15), 56 - 75 years (PID1091 V1.1)GMALL 08/2013 - ALL/LBL consolidation II in treatment failure/MRD persistence of T-ALL/T-LBL, 18 - 55 years (PID965 V2.0)GMALL 08/2013 - ALL/LBL consolidation III and V (week 24,34), 56 - 75 yrs (PID1090 V1.1)GMALL 08/2013 - ALL/LBL consolidation IV and VI (weeks 27, 35), 18 - 55 yrs (PID632 V2.1)GMALL 08/2013 - ALL/LBL Reinduction (Week 19), 18 - 55 years (PID636 V2.1)GMALL 08/2013 - ALL/LBL Reinduction (Week 19), 56 - 75 years (PID1096 V1.1)GMALL 08/2013 - ALL/LBL Pre-phase, 18 - 55 yrs (PID591 V2.0)GMALL 08/2013 - ALL/LBL Pre-phase, 56 - 75 yrs (PID1085 V1.0)GMALL 08/2013 - B-ALL/NHL 2002 regimen, Rituximab consolidation (PID784 V1.0)Nelarabine 1500, T-ALL/T-LBL (PID1922 V1.0)Nelarabine 650 / Peg-asparaginase 1500, T-ALL, maintenance, month 6, 7 (PID2083 V1.1)
