Search Back New search Go to resultsDiseaseMain groupCross-Sectional, Transplantation, Cellular TherapySolid TumorsProtocol groupSarcomasTransplantationDiseaseEwing SarcomaOsteosarcomaStem Cell Transplantation, AutologousSubgroupICD10C40.-C41.-C41.9Z94.80MeSHSarcoma, EwingSequenceEWING 2012 Arm A VIDEEWING 2012 Arm B VDC/IEChemotherapyChemo-substanceBusulfanCabozantinibCyclophosphamideDactinomycinDoxorubicinEtoposideIfosfamideIrinotecanMelphalanTemozolomideTopotecanTreosulfanVincristineChemo-substanceBusulfanCabozantinibCyclophosphamideDactinomycinDoxorubicinEtoposideIfosfamideIrinotecanMelphalanTemozolomideTopotecanTreosulfanVincristineChemo-substanceBusulfanCabozantinibCyclophosphamideDactinomycinDoxorubicinEtoposideIfosfamideIrinotecanMelphalanTemozolomideTopotecanTreosulfanVincristineChemo-substanceBusulfanCabozantinibCyclophosphamideDactinomycinDoxorubicinEtoposideIfosfamideIrinotecanMelphalanTemozolomideTopotecanTreosulfanVincristineNo. Substances1234 RadiotherapySupportive therapySupportive substanceAmphotericin BBalanced Crystalloid SolutionClonazepamCotrimoxazoleDexamethasoneFilgrastimFosaprepitantGranisetronHeparinMesnaPegfilgrastimUrsodeoxycholic acidZoledronic AcidSupportive substanceAmphotericin BBalanced Crystalloid SolutionClonazepamCotrimoxazoleDexamethasoneFilgrastimFosaprepitantGranisetronHeparinMesnaPegfilgrastimUrsodeoxycholic acidZoledronic AcidSupportive substanceAmphotericin BBalanced Crystalloid SolutionClonazepamCotrimoxazoleDexamethasoneFilgrastimFosaprepitantGranisetronHeparinMesnaPegfilgrastimUrsodeoxycholic acidZoledronic AcidSupportive substanceAmphotericin BBalanced Crystalloid SolutionClonazepamCotrimoxazoleDexamethasoneFilgrastimFosaprepitantGranisetronHeparinMesnaPegfilgrastimUrsodeoxycholic acidZoledronic AcidNo. Substances24567Protocol classificationTherapy classificationalternativecurrent standardIntensityhigh doseHigh dose myeloablativeStandard doseTherapy indicationFirst lineRelapse therapyseveral possibleTherapy phaseautologous stem cell transplantationConsolidationInductionseveral possibleTherapy intentioncurativepalliativeRisksAnemia Hb below 8g/dlColitisDiarrheaEmetogenicityEmetogenicity (ASCO)Emetogenicity (MASCC/ESMO)Febrile NeutropeniaHand-Foot SyndromeHepatotoxicityHypertensionHypokalemiaHypophosphatemiaHypothyroidismIncrease AminotransferasesInfectionsMucositisNeurotoxicityNeutropeniaPneumonitisProteinuriaRenal FailureThrombocytopenia below 50 000/µl only studiesPublicationAuthorAnderton JCasey ADirksen UHunold AItaliano AJürgens CLeDeley MDiseaseEwing Sarkom, Erstliniefortgeschrittenes oder refraktäres Ewing Sarkom, Rezidivtherapielokalisiertes Ewing-Sarkom, unter 50 JahreMetastasiertes oder lokal fortgeschrittenes Osteosarkom / Ewing Sarkom, > 12 Jahre, ECOG 0-1primär disseminiertes Ewing Sarkom, Alter unter 50rezidivierendes oder refraktäres Ewing Sarkom, ZweitlinieOriginDepartment of Pediatric Hematology and Oncology, University Children's Hospital, Muenster, GermanyEURO-EWING 99 clinical trialEuro Ewing 2012 protocolFunctional and Clinical Long-Term Outcome of Ewing Sarcoma Treatment (EWING 2008)Gustave Roussy Institute, Villejuif, France, Euro-EWING99-R1 TrialThe Memorial Sloan-Kettering ExperienceUniversity of Bordeaux, Bordeaux, France, CABONE trialProtocols in Revision 12 protocols foundProtocols under revision.Busulfan 0.8 / Melphalan 140, Ewing Sarcoma, Autologous Stem Cell Transplantation (PID571 V1.1)Cabozantinib 60, Osteosarcoma / Ewing Sarcoma (PID1869 V1.0)IE - Ifosfamide 1800 / Etoposide 100, Ewing Sarcoma (PID2068 V1.0)Irinotecan 20 / Temozolomide 100, Ewing Sarcoma (PID1199 V1.1)Melphalan 140 / Treosulfan 12, Ewing Sarcoma, Autologous Stem Cell Transplantation (PID1396 V2.1)Topotecan 0.75 / Cyclophosphamide 250, Ewing Sarcoma (PID1180 V1.0)VC - Vincristine 2 / Cyclophosphamide 1200, Ewing Sarcoma (PID2069 V1.0)VDC - Vincristine 2 / Doxorubicin 37.5 / Cyclophosphamide 1200, Ewing Sarcoma (PID2067 V1.0)Vincristine 1.5 / Dactinomycin 0.75 / Cyclophosphamide 1500, Ewing Sarcoma (PID50 V1.0)Vincristine 1.5 / Dactinomycin 0.75 / Ifosfamide 3, Ewing Sarcoma (PID74 V1.1)Vincristine 1.5 / Ifosfamide 3 / Doxorubicin 20 / Etoposide 150, Ewing Sarcoma (PID77 V1.1)Zoledronate 4, Ewing Sarcoma (PID2070 V1.0)
