Search Back New search Go to resultsDiseaseMain groupCross-Sectional, Transplantation, Cellular TherapyHematologic NeoplasmsProtocol groupAggressive LymphomasCellular TherapyIndolent LymphomasDiseaseCAR T-Cell TherapyChronic Lymphocytic Leukemia / Small Lymphocytic LymphomaNHL, B-Cell Type, Diffuse Large CellNHL, B-Cell Type, Follicular Grade I-IIIaNHL, B-Cell Type, Follicular grade IIIbSubgroupICD10C82.-C82.7C82.9C83.3C91.1-MeSHLymphoma, Large B-Cell, DiffuseSequenceChemotherapyChemo-substanceBendamustineCyclophosphamideFludarabineChemo-substanceBendamustineCyclophosphamideFludarabineChemo-substanceBendamustineCyclophosphamideFludarabineChemo-substanceBendamustineCyclophosphamideFludarabineNo. Substances12 RadiotherapySupportive therapySupportive substanceBalanced Crystalloid SolutionDexamethasoneGranisetronSupportive substanceBalanced Crystalloid SolutionDexamethasoneGranisetronSupportive substanceBalanced Crystalloid SolutionDexamethasoneGranisetronSupportive substanceBalanced Crystalloid SolutionDexamethasoneGranisetronNo. Substances3Protocol classificationTherapy classificationalternativecurrent standardIntensityStandard doseTherapy indicationseveral possibleTherapy phaseTherapy intentionRisksAnemia Hb below 8g/dlEmetogenicity (MASCC/ESMO)HypertensionLymphopeniaNeutropeniaThrombocytopenia below 50 000/µl only studiesPublicationAuthorLiu E Schuster SJDiseaseB-NHL, rezidiviert oder therapierefraktär, CD19- positiv, Lymphodepletion vor CAR T-Zell TherapieDLBCL, Rezidiv nach mind. 2 Vortherapien, ASCT ungeeignet oder bereits unterzogen, Lymphodepletion vor CAR-T-Zell TherapieDLBCL, Rezidiv nach mind. 2 Vortherapien, ASCT ungeeignet oder bereits unterzogen, Lymphodepletion vor CAR T-Zell TherapieOriginAbramson Cancer Center, University of Pennsylvania, Philadelphia, JULIET trialUniversity of Texas M.D. Anderson Cancer Center, HoustonProtocols in Revision 3 protocols foundProtocols under revision.Bendamustine 90, diffuse large B-non-Hodgkin Lymphoma, Lymphodepletion (PID1830 V1.0)Fludarabine 25 / Cyclophosphamide 250, diffuse large B-non-Hodgkin Lymphoma, Lymphodepletion (PID1829 V1.0)Fludarabine 30 / Cyclophosphamide 300, B-non-Hodgkin Lymphoma, Lymphodepletion (PID2471 V2.0)
