Search Back New search Go to resultsDiseaseMain groupHematological Diseases, Non-MalignantHematologic NeoplasmsProtocol groupAggressive LymphomasHemolytic DiseasesDiseaseNHL, B-Cell Type, Diffuse Large CellSubgroupmolecular high grade (MHG)non-GCBICD10C83.3MeSHLymphoma, Large B-Cell, DiffuseSequenceViPOR (OBIN1000/PRED100/IBRU560/LENA15/VNTC(50/200/600/800)), DLCBL, C1 (PID2666) -|- C2-6 (PID2677)ChemotherapyChemo-substanceIbrutinibLenalidomideObinutuzumabPrednisoloneVenetoclaxChemo-substanceIbrutinibLenalidomideObinutuzumabPrednisoloneVenetoclaxChemo-substanceIbrutinibLenalidomideObinutuzumabPrednisoloneVenetoclaxChemo-substanceIbrutinibLenalidomideObinutuzumabPrednisoloneVenetoclaxNo. Substances5 RadiotherapySupportive therapySupportive substanceAcetylsalicylic acidAllopurinolBalanced Crystalloid SolutionCotrimoxazoleDalteparinDimetindenPantoprazoleParacetamolPegfilgrastimSupportive substanceAcetylsalicylic acidAllopurinolBalanced Crystalloid SolutionCotrimoxazoleDalteparinDimetindenPantoprazoleParacetamolPegfilgrastimSupportive substanceAcetylsalicylic acidAllopurinolBalanced Crystalloid SolutionCotrimoxazoleDalteparinDimetindenPantoprazoleParacetamolPegfilgrastimSupportive substanceAcetylsalicylic acidAllopurinolBalanced Crystalloid SolutionCotrimoxazoleDalteparinDimetindenPantoprazoleParacetamolPegfilgrastimNo. Substances89Protocol classificationTherapy classificationalternativeIntensityStandard doseTherapy indicationRelapse therapyTherapy phaseTherapy intentionpalliativeRisksAnemia Hb below 8g/dlCardiotoxicityDiarrheaFebrile NeutropeniaHypokalemiaHypomagnesemiaHypophosphatemiaIncrease AminotransferasesNeutropeniaThrombocytopenia below 50 000/µlTumor Lysis Syndrome only studiesPublicationAuthorMelani CDiseaseRezidiviertes oder refraktäres diffus großzelliges Lymphom, ECOG 0-2OriginCenter for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, ViPORProtocols in Revision 2 protocols foundProtocols under revision.ViPOR - Obinutuzumab 1000 / Prednisolone 100 / Ibrutinib 560 / Lenalidomide 15 / Venetoclax (50/200/600/800), diffuse large B-non-Hodgkin lymphoma, cycle 1 (PID2666 V1.0)ViPOR - Obinutuzumab 1000 / Prednisolone 100 / Ibrutinib 560 / Lenalidomide 15 / Venetoclax 800, diffuse large B-cell non-Hodgkin Lymphoma, cycle 2-6 (PID2677 V1.0)
