Search Back New search Go to resultsDiseaseMain groupCross-Sectional, Transplantation, Cellular TherapyHematologic NeoplasmsSolid TumorsProtocol groupAggressive LymphomasNeuro-OncologyTransplantationDiseaseMalignant MeningitisNHL, CNS-NHLSubgroupLymphomatous MeningitisICD10C79.3C83.3MeSHCentral Nervous System NeoplasmsLymphoma, Non-HodgkinMeningeal CarcinomatosisSequenceFreiburg CNS-NHL StudyMATRIXMTRX8000/RITU375/TMZL150, CNS lymphoma, C1 (PID1859) -|- C2 (PID1860) -|- C3 (PID1861) -|- C4 (PID1864) -|- C5 (PID1865) -|- C6 (PID1866)R-MP (RITU375/MTRX3000/PRCR60), CNS Lymphoma, C1 (PID1191) -|- C2-3 (PID1030) -|- PRCR100, maint. (PID1031)RITU375/MTRX3500/PRCR100/VNCR2, CNS lymphoma, C1-3 (PID1896) -|- RITU375/CYTA3000, C4-6 (PID1901)RITU750/TMZL150, CNS-NHL, ind. (PID2437) -|- TMZL150, cons. (PID2438) -|- MTPR1, maint. (PID2439)ChemotherapyChemo-substanceCarboplatinCarmustineCytarabineDexamethasoneEtoposideIfosfamideMethotrexateMethylprednisoloneProcarbazineRituximabTemozolomideThiotepaVincristineChemo-substanceCarboplatinCarmustineCytarabineDexamethasoneEtoposideIfosfamideMethotrexateMethylprednisoloneProcarbazineRituximabTemozolomideThiotepaVincristineChemo-substanceCarboplatinCarmustineCytarabineDexamethasoneEtoposideIfosfamideMethotrexateMethylprednisoloneProcarbazineRituximabTemozolomideThiotepaVincristineChemo-substanceCarboplatinCarmustineCytarabineDexamethasoneEtoposideIfosfamideMethotrexateMethylprednisoloneProcarbazineRituximabTemozolomideThiotepaVincristineNo. Substances12345 RadiotherapySupportive therapySupportive substanceAciclovirAmphotericin BAprepitantBalanced Crystalloid SolutionCiprofloxacinCotrimoxazoleDexamethasoneDextrose 5%DimetindenFilgrastimFluconazoleFolinic acidFosaprepitantFurosemideGranisetronMesnaNaCl 0.9%ParacetamolPegfilgrastimPosaconazolePotassium chloridePrednisoloneSodium BicarbonateSupportive substanceAciclovirAmphotericin BAprepitantBalanced Crystalloid SolutionCiprofloxacinCotrimoxazoleDexamethasoneDextrose 5%DimetindenFilgrastimFluconazoleFolinic acidFosaprepitantFurosemideGranisetronMesnaNaCl 0.9%ParacetamolPegfilgrastimPosaconazolePotassium chloridePrednisoloneSodium BicarbonateSupportive substanceAciclovirAmphotericin BAprepitantBalanced Crystalloid SolutionCiprofloxacinCotrimoxazoleDexamethasoneDextrose 5%DimetindenFilgrastimFluconazoleFolinic acidFosaprepitantFurosemideGranisetronMesnaNaCl 0.9%ParacetamolPegfilgrastimPosaconazolePotassium chloridePrednisoloneSodium BicarbonateSupportive substanceAciclovirAmphotericin BAprepitantBalanced Crystalloid SolutionCiprofloxacinCotrimoxazoleDexamethasoneDextrose 5%DimetindenFilgrastimFluconazoleFolinic acidFosaprepitantFurosemideGranisetronMesnaNaCl 0.9%ParacetamolPegfilgrastimPosaconazolePotassium chloridePrednisoloneSodium BicarbonateNo. Substances156789111213141516Protocol classificationTherapy classificationalternativecurrent standardstudy analogIntensityhigh doseStandard doseTherapy indicationFirst lineSecond lineTherapy phaseautologous stem cell transplantationconditioningConsolidationInductionMaintenanceTherapy intentioncurativedisease controlpalliativeRisksAnemia Hb below 8g/dlCardiotoxicityDiarrheaEmetogenicityEmetogenicity (ASCO)Emetogenicity (MASCC/ESMO)FatigueFebrile NeutropeniaHepatotoxicityHyperglycemiaHypokalemiaHyponatremiaIncrease AminotransferasesInfectionsLeukopeniaLymphopeniaMucositisNephrotoxicityNeuropathyNeutropeniaPneumonitisPyrexiaRashRenal FailureThrombocytopenia below 50 000/µlThromboembolic Event only studiesPublicationAuthorFerreri AJFritsch KHouillier CIllerhaus GNayak LRubenstein JLDiseaseErstdiagnose eines primären NHL des ZNS, 18-65 Jahreneudiagnostiziertes primäres ZNS-Lymphom, > 60 JahreNeu diagnostiziertes primäres ZNS-Lymphom, > 66 Jahre, Karnofsky > 70neudiagnostiziertes primäres ZNS-Lymphom, > 66 Jahre, Karnofsky > 70neudiagnostiziertes primäres ZNS-Lymphom, ECOG 0-2Neudiagnostiziertes primäres ZNS-Lymphom, ECOG 0-2primäres ZNS-Lymphom, Rezidivtherapie, Karnofsky Status größer 60%primäres ZNS-NHL, ErstdiagnoseZentrales B-NHL, Erstlinie, ECOG 0-3OriginAlbert-Ludwigs University, Freiburg, Germany, Freiburger ZNS-NHL ProtokollDepartment of Haematology, Oncology and Stem Cell Transplantation, University Hospital Freiburg, Primain StudyDepartment of Neurology, Memorial Sloan-Kettering Cancer Center, New York, USA, North American Brain Tumor ConsortiumHelen Diller Comprehensive Cancer Center, University of California, San Francisco, CALGB 50202 (Alliance 50202)IRCCS San Raffaele Scientific Institute, Milan, Italy, IELSG32 trialMATRix / IELSG43 StudieUniversites Paris, Paris, France, LOC network studyProtocols in Revision 23 protocols foundProtocols under revision.Carmustine 400 / Thiotepa 5, consolidation before autologous Stem Cell Transplantation, CNS- Non-Hodgkin Lymphoma (PID890 V2.1)Cytarabine 2000 / Etoposide 5, CNS Lymphoma, cycle 6 (PID1866 V1.0)Methotrexate 500/3000, Malignant Meningitis (PID1000 V1.0)Methotrexate 8000 / Rituximab 375 / Temozolomide 150, CNS Lymphoma, cycle 1 (PID1859 V1.1)Methotrexate 8000 / Rituximab 375 / Temozolomide 150, CNS Lymphoma, cycle 2 (PID1860 V1.3)Methotrexate 8000 / Temozolomide 150, CNS Lymphoma, cycle 3 (PID1861 V1.3)Methotrexate 8000 / Temozolomide 150, CNS Lymphoma, cycle 4 (PID1864 V1.3)Methotrexate 8000 / Temozolomide 150, CNS Lymphoma, cycle 5 (PID1865 V1.3)Methylprednisolone 1000, CNS Lymphoma, maintenance. (PID2439 V1.0)Rituximab 375 / Carboplatin 300 / Ifosfamide 1.5 / Etoposide 100 / Dexamethasone 40, CNS- Non-Hodgkin Lymphoma, consolidation (PID831 V1.1)Rituximab 375 / Carmustine 400 / Thiotepa 5, CNS- Non-Hodgkin Lymphoma, conditioning, cycle 5 (PID1883 V1.0)Rituximab 375 / Cytarabine 3000 / Thiotepa 40, CNS- Non-Hodgkin Lymphoma, induction, cycle 3 (PID1881 V1.0)Rituximab 375 / Cytarabine 3000 / Thiotepa 40, CNS- Non-Hodgkin Lymphoma, Induction, Cycle 4 (PID1882 V1.0)Rituximab 375 / Cytarabine 3000, CNS- lymphoma, cycle 4-6 (PID1901 V1.0)Rituximab 375 / Methotrexate 3000 / Procarbazine 60 - Procarbazine 100, maintenance, CNS- Lymphoma (PID1031 V1.2)Rituximab 375 / Methotrexate 3000 / Procarbazine 60, CNS lymphoma, cycle 1 (PID1191 V1.3)Rituximab 375 / Methotrexate 3000 / Procarbazine 60, CNS- lymphoma, cycle 2-3 (PID1030 V2.3)Rituximab 375 / Methotrexate 3500 / Procarbazine 100 / Vincristine 2, CNS Lymphoma, cycle 1-3 (PID1896 V1.2)Rituximab 375 / Methotrexate 500/3000 / Cytarabine 2000 / Thiotepa 30, CNS- Non-Hodgkin Lymphoma, induction (PID703 V2.1)Rituximab 375 / Methotrexate 8000, CNS- Non-Hodgkin Lymphoma, induction, cycle 1 (PID1879 V1.2)Rituximab 375 / Methotrexate 8000, CNS- Non-Hodgkin Lymphoma, induction, cycle 2 (PID1880 V1.2)Rituximab 750 / Temozolomide 150, CNS Lymphoma, Induction (PID2437 V1.0)Temozolomide 150, CNS Lymphoma, consolidation (PID2438 V1.0)
