Search Back New search Go to resultsDiseaseMain groupCross-Sectional, Transplantation, Cellular TherapySolid TumorsProtocol groupNeuro-OncologyradiotherapyDiseaseGlioblastomaSubgroupmethylated MGMT PromoterICD10C71.-MeSHGlioblastomaSequenceTMZL75/Radiation, Glioblastoma (PID546) -|- TMZL150 after Radio-Chemo, C1 (PID547) -|- TMZL200 C2-6 (PID548)TMZL75/Radiation, Glioblastoma, C1 (PID2472) -|- C2 (PID2473) -|- C3-12 (PID2474).ChemotherapyChemo-substanceInterferon alpha-2aLomustineTemozolomideChemo-substanceInterferon alpha-2aLomustineTemozolomideChemo-substanceInterferon alpha-2aLomustineTemozolomideChemo-substanceInterferon alpha-2aLomustineTemozolomideNo. Substances12 RadiotherapySupportive therapySupportive substanceCotrimoxazoleDexamethasoneGranisetronSupportive substanceCotrimoxazoleDexamethasoneGranisetronSupportive substanceCotrimoxazoleDexamethasoneGranisetronSupportive substanceCotrimoxazoleDexamethasoneGranisetronNo. Substances13Protocol classificationTherapy classificationalternativecurrent standardIntensityStandard doseTherapy indicationFirst lineTherapy phaseTherapy intentionpalliativeRisksAnemia Hb below 8g/dlConstipationEmetogenicity (ASCO)HepatotoxicityIncrease AminotransferasesInfectionsLeukopeniaNeutropeniaPyrexiaSeizuresThrombocytopenia below 50 000/µlThromboembolic Event only studiesPublicationAuthorGuo CHerrlinger UStupp RDiseaseGlioblastom, ECOG 0-2neu diagnostiziertes Glioblastom, Karnofsky > 70%Neudiagnostiziertes high grade Gliom, Erstlinie, Karnofsky größer 60%OriginDepartment of Neurosurgery andNeurooncology, Sun Yat-Sen University Cancer Center, State Key Laboratory of Oncology, South ChinaEORTC, NCICNeurooncology Working Group of the German Cancer Society, CeTeG/NOA–09Protocols in Revision 5 protocols foundProtocols under revision.Interferon Alpha-2a 3Mio / Temozolomide 150, cycle 2 (PID2473 V1.1)Interferon Alpha-2a 3Mio / Temozolomide 200, Glioblastoma, Cycle 3-12 (PID2474 V1.0)Lomustine 100 / Temozolomide 100 / Radiation, Glioblastoma (PID488 V1.2)Temozolomide 75 / Radiation, Glioblastoma (PID546 V1.1)Temozolomide 75 / Radiation, Glioblastoma, Cycle 1 (PID2472 V1.0)