{"text_format":"1","workbook":"xlsx","n_sheets":5,"sheets":["Übersicht","Zyklusdiagramm","Tag 1","Tag 8","Tag 15"],"not_rendered":{"charts":0,"images":1,"macros":1,"external_links":0,"defined_names":433,"comments":5,"pivot_tables":0},"unopened":[],"bounds":{"document_bytes":16777216,"sheet_cells":100000,"rows_first":2000,"rows_last":500,"rows_between":2000,"halvings":0,"cell_chars":16384,"cell_head_chars":4096},"cells_cut":0,"cells_raw":0,"read":"whole","date_system":"1900"}

{"sheet":"Übersicht","index":0,"n_rows":78,"n_cols":11,"rows_kept":78,"cut":false,"hidden":false,"merged":[[72,2,72,4],[0,0,7,0],[0,1,0,9],[8,2,8,10],[10,2,10,10],[7,2,7,10],[1,1,1,4],[2,2,2,4],[15,2,15,10],[9,2,9,10],[11,2,11,10],[14,2,14,10],[12,2,12,10],[13,2,13,10]]}
["Entwurf","Atezolizumab 1200 / Carboplatin 6 / Nab-Paclitaxel 100, nichtkleinzelliges Lungenkarzinom (PID=1238 V1.1)",null,null,null,null,null,null,null,null,{"$f":"\"Übersicht Z\" & Zyklusnummer","v":"Übersicht Z1"}]
[null,"Doe, John",null,null,null,"geb.","1950-01-01","Alter",{"$f":"IF(PatientGeboren=0,\"\",DATEDIF(PatientGeboren,NOW(),\"y\") & \"J \" & MOD(DATEDIF(PatientGeboren,NOW(),\"m\"),12) & \"M\")","v":"71J 8M"},"Geschlecht","m"]
[null,"Diagnose","Nichtkleinzelliges Lungenkarzinom",null,null,"Stadium","IV","Therapiemodus","Erstlinie","Erstdiagnose","2021-09-06"]
[null,"Größe",170,"Gewicht",75,"KOF",{"$f":"KG^0.425*GroesseCM^0.725/139.315","v":1.8619954939793939},"Infusionsarm","rechts","Pat-ID",1]
[null,"Serum-Kreatinin",0.8,"Datum","2021-09-06",{"$f":"\"GFR \" & shortGFR(sGFR)","v":"GFR NM"},{"$f":"fGFR(KG,GroesseCM,PatientAlter,PatientGeschlecht,PatientSerumKreatinin)","v":94.329553850453848},"Port","rechts","Auftragsnummer",1]
[null,"Zyklus Nr.",1,"von",6,null,21,{"$f":"ROUND((NOW()-PatientGeboren) / 365,0)","v":72}]
[null,"erster Tag","2021-09-06","Intervalltage",21,"Zyklusende",{"$f":"IF(OR(ISBLANK(Therapiebeginn),ISBLANK(IntervallTage)), \"\", Therapiebeginn+IntervallTage-1)","v":"2021-09-26"},"erster Zyklus",null,"nächster Zyklus",{"$f":"IF(OR(ISBLANK(Therapiebeginn),ISBLANK(IntervallTage),EmpfZyklen=1),\"\",Therapiebeginn+IntervallTage)","v":"2021-09-27"}]
[null,"Hinweise"]
[null,"Risiken","Emetogenität (MASCC/ESMO): hoch (> 90%); Neutropenie: sehr hoch (> 41%, °3-4: 44%); Thrombozytopenie unter 50 000/µl: sehr hoch (> 41%, °3-4: 45%); Anämie Hb unter 8g/dl: hoch (16% - 30%, °3-4: 29%); Diarrhoe: CTC AE (°3-4: 5%); Abgeschlagenheit: CTC AE (°3-4: 6%); Nausea: CTC AE (°3-4: 3%)"]
[null,"Klassifikation","alternativ; Intensität: Standard-Dosis; Modus: Erstlinie; Intention: palliativ"]
[null,"Indikationen","Lungenkarzinom, nichtkleinzelliges (nicht-plattenepithelial)"]
[null,"Empfehlungen","Onkopedia, ESMO, NCCN"]
[null,"Herkunft","Kooperation: Thoracic Oncology Program, Swedish Cancer Institute, Seattle, USA, IMpower130; ursprünglicher Autor: West H"]
[null,"Literatur","West H, Lancet Oncol 2019 May 20;"]
[null,null,"Arbour KC, J Clin Oncol 2018 10 01;36(28):2872-2878"]
[null,null,"Della Corte CM, ESMO Open 2019;4(1):e000477"]
[null,"Dateipfad",{"$f":"optiFilename()","v":"c:\\Protokolle"}]
[]
[null,"Tag",1,8,15]
[null,"Datum",{"$f":"Therapiebeginn","v":"2021-09-06"},{"$f":"PDateOV_1+7","v":"2021-09-13"},{"$f":"PDateOV_8+7","v":"2021-09-20"}]
[null,"Flüssigkeitszufuhr: Jonosteril"]
[null,"Jonosteril (i.v.)",{"$f":"PMSID_19550_1_A_D","v":500},{"$f":"PMSID_19550_8_A_D","v":0},{"$f":"PMSID_19550_15_A_D","v":0}]
[null,"% Dosis",1,0,0]
[null,"normale Dosierung",500,500,500]
[]
[null,"Jonosteril (i.v.)",{"$f":"PMSID_19551_1_A_D","v":0},{"$f":"PMSID_19551_8_A_D","v":500},{"$f":"PMSID_19551_15_A_D","v":500}]
[null,"% Dosis",0,1,1]
[null,"normale Dosierung",500,500,500]
[]
[null,"Antiemese: Emetogenität hoch (CRBP), FOSAP, PALO i.v., ohne DEXA i.v."]
[null,"Fosaprepitant (i.v.)",{"$f":"PMSID_19414_1_A_D","v":150},{"$f":"PMSID_19414_8_A_D","v":0},{"$f":"PMSID_19414_15_A_D","v":0}]
[null,"% Dosis",1,0,0]
[null,"normale Dosierung",150,150,150]
[]
[null,"Palonosetron (i.v.)",{"$f":"PMSID_21866_1_A_D","v":250},{"$f":"PMSID_21866_8_A_D","v":0},{"$f":"PMSID_21866_15_A_D","v":0}]
[null,"% Dosis",1,0,0]
[null,"normale Dosierung",250,250,250]
[]
[null,"Granisetron (i.v.)",{"$f":"PMSID_19416_1_A_D","v":0},{"$f":"PMSID_19416_8_A_D","v":1},{"$f":"PMSID_19416_15_A_D","v":1}]
[null,"% Dosis",0,1,1]
[null,"normale Dosierung",1,1,1]
[]
[null,"Medikamentöse Tumortherapie: ATEZ1200/CRBP6/NPAC100"]
[null,"Atezolizumab (i.v.)",{"$f":"PMSID_19410_1_A_D","v":1200},{"$f":"PMSID_19410_8_A_D","v":0},{"$f":"PMSID_19410_15_A_D","v":0}]
[null,"% Dosis",1,0,0]
[null,"normale Dosierung",1200,1200,1200]
[]
[null,"Carboplatin (i.v.)",{"$f":"PMSID_19411_1_A_D","v":715.97732310272306},{"$f":"PMSID_19411_8_A_D","v":0},{"$f":"PMSID_19411_15_A_D","v":0}]
[null,"% Dosis",1,0,0]
[null,"normale Dosierung",6,6,6]
[]
[null,"Nab-Paclitaxel (i.v.)",{"$f":"PMSID_19412_1_A_D","v":186.19954939793939},{"$f":"PMSID_19412_8_A_D","v":186.19954939793939},{"$f":"PMSID_19412_15_A_D","v":186.19954939793939}]
[null,"% Dosis",1,1,1]
[null,"normale Dosierung",100,100,100]
[]
[null,"Sonstige Therapie: "]
[null,"[Substanznamen eingeben]",{"$f":"PMSID_1_1_A_D","v":0},{"$f":"PMSID_1_8_A_D","v":0},{"$f":"PMSID_1_15_A_D","v":0}]
[null,"p.o.",0,0,0]
[null,"mg",0,0,0]
[]
[null,"[Substanznamen eingeben]",{"$f":"PMSID_2_1_A_D","v":0},{"$f":"PMSID_2_8_A_D","v":0},{"$f":"PMSID_2_15_A_D","v":0}]
[null,"p.o.",0,0,0]
[null,"mg",0,0,0]
[]
[null,"[Substanznamen eingeben]",{"$f":"PMSID_3_1_A_D","v":0},{"$f":"PMSID_3_8_A_D","v":0},{"$f":"PMSID_3_15_A_D","v":0}]
[null,"p.o.",0,0,0]
[null,"mg",0,0,0]
[]
[null,"[Substanznamen eingeben]",{"$f":"PMSID_4_1_A_D","v":0},{"$f":"PMSID_4_8_A_D","v":0},{"$f":"PMSID_4_15_A_D","v":0}]
[null,"p.o.",0,0,0]
[null,"mg",0,0,0]
[]
[null,"Kontrollen"]
[null,"Echokardiografie, EKG"]
[null,"Tag 1: TSH, fT3, fT4"]
[null,"Tag 1: GOT, GPT, GGT, Bilirubin, AP, Cholinesterase"]
[null,"Tag 1: Glomeruläre Filtrationsrate (GFR)"]
[null,"Blutbild: an Tag 1 und in Folge wöchentlich"]

{"sheet":"Zyklusdiagramm","index":1,"n_rows":44,"n_cols":39,"rows_kept":44,"cut":false,"hidden":false,"merged":[[33,2,33,38],[40,2,40,38],[41,2,41,38],[42,2,42,38],[43,2,43,38],[9,2,9,8],[9,9,9,15],[9,16,9,22],[1,35,1,38],[1,21,1,25],[1,26,1,29],[4,21,4,25],[2,26,2,29],[1,30,1,34],[2,30,2,34],[3,30,3,34],[4,30,4,34],[3,35,3,38],[2,35,2,38],[2,21,2,25],[4,26,4,29],[3,21,3,25],[3,26,3,29],[4,9,4,12],[5,2,5,4],[4,13,4,16],[5,9,5,12],[5,13,5,16],[4,2,4,4],[1,13,1,16],[3,5,3,8],[3,13,3,16],[2,13,2,16],[2,2,2,12],[0,0,7,0],[5,35,5,38],[5,17,5,20],[5,5,5,8],[5,30,5,34],[5,26,5,29],[5,21,5,25],[4,17,4,20],[4,5,4,8],[0,1,0,32],[3,9,3,12],[3,2,3,4],[1,17,1,20],[2,17,2,20],[3,17,3,20],[1,1,1,12]]}
["Entwurf",{"$f":"Protokollname","v":"Atezolizumab 1200 / Carboplatin 6 / Nab-Paclitaxel 100, nichtkleinzelliges Lungenkarzinom (PID=1238 V1.1)"},null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,{"$f":"\"Zyklusdiagramm Z\" & Zyklusnummer","v":"Zyklusdiagramm Z1"}]
[null,{"$f":"IF(PatientName=\"\",\"\",PatientName)","v":"Doe, John"},null,null,null,null,null,null,null,null,null,null,null,"geb.",null,null,null,{"$f":"PatientGeboren","v":"1950-01-01"},null,null,null,"Alter",null,null,null,null,{"$f":"DATEDIF(PatientGeboren,NOW(),\"y\")&\"J \"&MOD(DATEDIF(PatientGeboren,NOW(),\"m\"),12)&\"M\"","v":"71J 8M"},null,null,null,"Geschlecht",null,null,null,null,{"$f":"PatientGeschlecht","v":"m"}]
[null,"Diagnose",{"$f":"IF(Diagnose=\"\",\"\",Diagnose)","v":"Nichtkleinzelliges Lungenkarzinom"},null,null,null,null,null,null,null,null,null,null,"Stadium",null,null,null,{"$f":"IF(Stadium=\"\",\"\",Stadium)","v":"IV"},null,null,null,"Therapiemodus",null,null,null,null,{"$f":"IF(Therapiemodus<>\"\",Therapiemodus,\"\")","v":"Erstlinie"},null,null,null,"Pat-ID",null,null,null,null,{"$f":"IF(PatientID=\"\",\"\",PatientID)","v":1}]
[null,"Größe",{"$f":"GroesseCM","v":170},null,null,"Gewicht",null,null,null,{"$f":"KG","v":75},null,null,null,"KOF",null,null,null,{"$f":"KOF","v":1.8619954939793939},null,null,null,"Infusionsarm",null,null,null,null,{"$f":"PatientInfusionsarm","v":"rechts"},null,null,null,"Auftragsnr.",null,null,null,null,{"$f":"IF(Auftragsnummer=\"\",\"\",Auftragsnummer)","v":1}]
[null,"Serum-Kreatinin",{"$f":"PatientSerumKreatinin","v":0.8},null,null,{"$f":"\"GFR \" & shortGFR(sGFR)","v":"GFR NM"},null,null,null,{"$f":"PatientKreatininClearance","v":94.329553850453848},null,null,null,"Datum",null,null,null,{"$f":"PatientSerumKreatininDatum","v":"2021-09-06"},null,null,null,"Port",null,null,null,null,{"$f":"PatientPort","v":"rechts"}]
[null,"Zyklus Nr",{"$f":"Zyklusnummer","v":1},null,null,"von",null,null,null,{"$f":"EmpfZyklen","v":6},null,null,null,"Intervalltage",null,null,null,{"$f":"IntervallTage","v":21},null,null,null,"erster Tag",null,null,null,null,{"$f":"Therapiebeginn","v":"2021-09-06"},null,null,null,"nächster Zyklus",null,null,null,null,{"$f":"nächsterZyklus","v":"2021-09-27"}]
[null,"Dateipfad",{"$f":"Dateipfad","v":"c:\\Protokolle"}]
[]
[]
[null,null,{"$f":"\"Woche \" & IF(C12<0,C12/7,I12/7)","v":"Woche 1"},null,null,null,null,null,null,{"$f":"\"Woche \" & IF(J12<0,J12/7,P12/7)","v":"Woche 2"},null,null,null,null,null,null,{"$f":"\"Woche \" & IF(Q12<0,Q12/7,W12/7)","v":"Woche 3"}]
[null,null,{"$f":"PDateOV_1","v":"2021-09-06"},{"$f":"C11+1","v":"2021-09-07"},{"$f":"D11+1","v":"2021-09-08"},"2021-09-09","2021-09-10","2021-09-11","2021-09-12",{"$f":"PDateOV_8","v":"2021-09-13"},"2021-09-14","2021-09-15","2021-09-16","2021-09-17","2021-09-18","2021-09-19",{"$f":"PDateOV_15","v":"2021-09-20"},"2021-09-21","2021-09-22","2021-09-23","2021-09-24","2021-09-25","2021-09-26"]
[null,"Flüssigkeitszufuhr",1,{"$f":"IF(C12=-1,1,C12+1)","v":2},{"$f":"IF(D12=-1,1,D12+1)","v":3},4,5,6,7,8,9,10,11,12,13,14,15,16,17,18,19,20,21]
[null,"Jonosteril (i.v.)"]
[null,"Jonosteril (i.v.)"]
[null,"Antiemese"]
[null,"Fosaprepitant (i.v.)"]
[null,"Palonosetron (i.v.)"]
[null,"Granisetron (i.v.)"]
[null,"Medikamentöse Tumortherapie"]
[null,"Atezolizumab (i.v.)"]
[null,"Carboplatin (i.v.)"]
[null,"Nab-Paclitaxel (i.v.)"]
[null,"Sonstige Therapie"]
[null,"[Substanznamen eingeben]"]
[null,"[Substanznamen eingeben]"]
[null,"[Substanznamen eingeben]"]
[null,"[Substanznamen eingeben]"]
[]
[]
[]
[]
[]
[]
[null,"Kontrollen"]
[null,"Echokardiografie, EKG"]
[null,"Tag 1: TSH, fT3, fT4"]
[null,"Tag 1: GOT, GPT, GGT, Bilirubin, AP, Cholinesterase"]
[null,"Tag 1: Glomeruläre Filtrationsrate (GFR)"]
[null,"Blutbild: an Tag 1 und in Folge wöchentlich"]
[]
[null,"Dosierungsbemerkungen"]
[null,"Jonosteril","oder vergleichbare isotone kristalloide Elektrolytlösung"]
[null,"Jonosteril","oder vergleichbare isotone kristalloide Elektrolytlösung"]
[null,"Atezolizumab","Wenn die erste Infusion gut vertragen wurde, kann die zweite Infusion über 30 Minuten erfolgen."]

{"sheet":"Tag 1","index":2,"n_rows":37,"n_cols":12,"rows_kept":37,"cut":false,"hidden":false,"merged":[[35,6,35,7],[35,8,35,9],[36,6,36,7],[36,8,36,9],[37,6,37,7],[37,8,37,9],[32,6,32,7],[32,8,32,9],[33,6,33,7],[33,8,33,9],[34,6,34,7],[34,8,34,9],[28,6,28,7],[28,8,28,9],[30,6,30,7],[30,8,30,9],[31,6,31,7],[31,8,31,9],[25,6,25,7],[25,8,25,9],[26,6,26,7],[26,8,26,9],[27,6,27,7],[27,8,27,9],[21,6,21,7],[21,8,21,9],[23,6,23,7],[23,8,23,9],[24,6,24,7],[24,8,24,9],[18,6,18,7],[18,8,18,9],[19,6,19,7],[19,8,19,9],[20,6,20,7],[20,8,20,9],[14,6,14,7],[14,8,14,9],[16,6,16,7],[16,8,16,9],[17,6,17,7],[17,8,17,9],[11,6,11,7],[11,8,11,9],[12,6,12,7],[12,8,12,9],[13,6,13,7],[13,8,13,9],[0,0,7,0],[0,1,0,9],[1,1,1,5],[2,3,2,5],[9,6,9,7],[9,8,9,9]]}
["Entwurf",{"$f":"Protokollname","v":"Atezolizumab 1200 / Carboplatin 6 / Nab-Paclitaxel 100, nichtkleinzelliges Lungenkarzinom (PID=1238 V1.1)"},null,null,null,null,null,null,null,null,null,{"$f":"\"Z\" & Zyklusnummer & \"/d\" & F9","v":"Z1/d1"}]
[null,{"$f":"IF(PatientName=\"\",\"\",PatientName)","v":"Doe, John"},null,null,null,null,"geb.:",{"$f":"PatientGeboren","v":"1950-01-01"},"Alter",{"$f":"DATEDIF(PatientGeboren,NOW(),\"y\")&\"J \"&MOD(DATEDIF(PatientGeboren,NOW(),\"m\"),12)&\"M\"","v":"71J 8M"},"Geschlecht",{"$f":"PatientGeschlecht","v":"m"}]
[null,null,"Diagnose",{"$f":"IF(Diagnose=\"\",\"-\",Diagnose)","v":"Nichtkleinzelliges Lungenkarzinom"},null,null,"Stadium",{"$f":"IF(Stadium=\"\",\"\",Stadium)","v":"IV"},"Therapiemodus",{"$f":"IF(Therapiemodus<>\"\",Therapiemodus,\"\")","v":"Erstlinie"},"Erstdiagnose",{"$f":"IF(ErstdiagnoseDatum,ErstdiagnoseDatum,\"\")","v":"2021-09-06"}]
[null,null,"Größe",{"$f":"GroesseCM","v":170},"Gewicht",{"$f":"KG","v":75},"KOF",{"$f":"KG_1^0.425*GroesseCM_1^0.725/139.315","v":1.8619954939793939},"Infusionsarm",{"$f":"PatientInfusionsarm","v":"rechts"},"Pat-ID",{"$f":"IF(PatientID=\"\",\"\",PatientID)","v":1}]
[null,null,"Serum-Kreatinin",{"$f":"PatientSerumKreatinin","v":0.8},"Datum",{"$f":"PatientSerumKreatininDatum","v":"2021-09-06"},{"$f":"\"GFR \" & shortGFR(sGFR)","v":"GFR NM"},{"$f":"fGFR(F4,D4,PatientAlter,PatientGeschlecht,D5)","v":94.329553850453848},"Port",{"$f":"PatientPort","v":"rechts"},"Auftragsnummer",{"$f":"IF(Auftragsnummer=\"\",\"\",Auftragsnummer)","v":1}]
[null,null,"erster Tag",{"$f":"Therapiebeginn","v":"2021-09-06"},"Anzahl Zyklen",{"$f":"EmpfZyklen","v":6},"Intervalltage",{"$f":"IntervallTage","v":21},"erster Zyklus",{"$f":"DatumErsterZyklus","v":"00:00:00"},"nächster Zyklus",{"$f":"nächsterZyklus","v":"2021-09-27"}]
[null,null,"Dateipfad",{"$f":"Dateipfad","v":"c:\\Protokolle"}]
[]
[null,null,"Therapiedatum",{"$f":"PDateOV_1","v":"2021-09-06"},"Zyklustag:",1,"Zyklus: ",{"$f":"Zyklusnummer","v":1},"Uhrzeit:","00:00:00"]
[null,"Appl. Art","Medikament, Substanz","Dosis, Einheit","normale Dosierung","% Anteil Normaldosis","Trägerlsg. Volumen",null,"Ablauf",null,"Dauer","Hdz. Arzt\nUhrzeit"]
[null,"Flüssigkeitszufuhr: Jonosteril",null,null,null,null,null,null,null,null,null,"Zugangsart: peripher venös"]
[null,"i.v.","Jonosteril",{"$f":"PMSID_19550_1_B_D*1*PMSID_19550_1_F_D","v":500},500,1,"-",null,"60 min vor Atezolizumab (d1)",null,"60 min"]
[]
[null,"i.v.","Jonosteril",{"$f":"PMSID_19551_1_B_D*1*PMSID_19551_1_F_D","v":0},500,0,"-",null,"60 min vor Nab-Paclitaxel (d8,15)",null,"60 min"]
[]
[null,"Antiemese: Emetogenität hoch (CRBP), FOSAP, PALO i.v., ohne DEXA i.v.",null,null,null,null,null,null,null,null,null,"Zugangsart: peripher venös"]
[null,"i.v.","Fosaprepitant",{"$f":"PMSID_19414_1_B_D*1*PMSID_19414_1_F_D","v":150},150,1,"NaCl 0,9%, 150 ml",null,"30 min vor Atezolizumab (d1)",null,"20 min"]
[]
[null,"i.v.","Palonosetron",{"$f":"PMSID_21866_1_B_D*PMSID_21866_1_F_D","v":250},250,1,"NaCl 0,9%, 50 ml",null,"30 min vor Atezolizumab (d1)",null,"5 min"]
[]
[null,"i.v.","Granisetron",{"$f":"PMSID_19416_1_B_D*1*PMSID_19416_1_F_D","v":0},1,0,"NaCl 0,9%, 50 ml",null,"15 min vor Nab-Paclitaxel (d8,15)",null,"5 min"]
[]
[null,"Medikamentöse Tumortherapie: ATEZ1200/CRBP6/NPAC100",null,null,null,null,null,null,null,null,null,"Zugangsart: peripher venös"]
[null,"i.v.","Atezolizumab",{"$f":"PMSID_19410_1_B_D*1*PMSID_19410_1_F_D","v":1200},1200,1,"NaCl 0,9%, 250 ml",null,"Reihenfolge",null,"60 min"]
[]
[null,"i.v.","Carboplatin",{"$f":"( 25 + fGFR(KG_1, GroesseCM, PatientAlter, PatientGeschlecht, SerumKreatinin_1) )* PMSID_19411_1_B_D*PMSID_19411_1_F_D","v":715.97732310272306},6,1,"Glucose 5%, 250 ml",null,"Reihenfolge",null,"30 min"]
[]
[null,"i.v.","Nab-Paclitaxel",{"$f":"PMSID_19412_1_B_D*KOF_1*PMSID_19412_1_F_D","v":186.19954939793939},100,1,"-",null,"Reihenfolge",null,"30 min"]
[]
[null,"Sonstige Therapie: ",null,null,null,null,null,null,null,null,null,"Zugangsart: Keine Angabe"]
[null,"p.o.",null,{"$f":"PMSID_1_1_B_D*PMSID_1_1_F_D","v":0},0,0,"-",null,"",null,"0 min"]
[]
[null,"p.o.",null,{"$f":"PMSID_2_1_B_D*PMSID_2_1_F_D","v":0},0,0,"-",null,"",null,"0 min"]
[]
[null,"p.o.",null,{"$f":"PMSID_3_1_B_D*PMSID_3_1_F_D","v":0},0,0,"-",null,"",null,"0 min"]
[]
[null,"p.o.",null,{"$f":"PMSID_4_1_B_D*PMSID_4_1_F_D","v":0},0,0,"-",null,"",null,"0 min"]

{"sheet":"Tag 8","index":3,"n_rows":37,"n_cols":12,"rows_kept":37,"cut":false,"hidden":false,"merged":[[35,6,35,7],[35,8,35,9],[36,6,36,7],[36,8,36,9],[37,6,37,7],[37,8,37,9],[32,6,32,7],[32,8,32,9],[33,6,33,7],[33,8,33,9],[34,6,34,7],[34,8,34,9],[28,6,28,7],[28,8,28,9],[30,6,30,7],[30,8,30,9],[31,6,31,7],[31,8,31,9],[25,6,25,7],[25,8,25,9],[26,6,26,7],[26,8,26,9],[27,6,27,7],[27,8,27,9],[21,6,21,7],[21,8,21,9],[23,6,23,7],[23,8,23,9],[24,6,24,7],[24,8,24,9],[18,6,18,7],[18,8,18,9],[19,6,19,7],[19,8,19,9],[20,6,20,7],[20,8,20,9],[14,6,14,7],[14,8,14,9],[16,6,16,7],[16,8,16,9],[17,6,17,7],[17,8,17,9],[11,6,11,7],[11,8,11,9],[12,6,12,7],[12,8,12,9],[13,6,13,7],[13,8,13,9],[0,0,7,0],[0,1,0,9],[1,1,1,5],[2,3,2,5],[9,6,9,7],[9,8,9,9]]}
["Entwurf",{"$f":"Protokollname","v":"Atezolizumab 1200 / Carboplatin 6 / Nab-Paclitaxel 100, nichtkleinzelliges Lungenkarzinom (PID=1238 V1.1)"},null,null,null,null,null,null,null,null,null,{"$f":"\"Z\" & Zyklusnummer & \"/d\" & F9","v":"Z1/d8"}]
[null,{"$f":"IF(PatientName=\"\",\"\",PatientName)","v":"Doe, John"},null,null,null,null,"geb.:",{"$f":"PatientGeboren","v":"1950-01-01"},"Alter",{"$f":"DATEDIF(PatientGeboren,NOW(),\"y\")&\"J \"&MOD(DATEDIF(PatientGeboren,NOW(),\"m\"),12)&\"M\"","v":"71J 8M"},"Geschlecht",{"$f":"PatientGeschlecht","v":"m"}]
[null,null,"Diagnose",{"$f":"IF(Diagnose=\"\",\"-\",Diagnose)","v":"Nichtkleinzelliges Lungenkarzinom"},null,null,"Stadium",{"$f":"IF(Stadium=\"\",\"\",Stadium)","v":"IV"},"Therapiemodus",{"$f":"IF(Therapiemodus<>\"\",Therapiemodus,\"\")","v":"Erstlinie"},"Erstdiagnose",{"$f":"IF(ErstdiagnoseDatum,ErstdiagnoseDatum,\"\")","v":"2021-09-06"}]
[null,null,"Größe",{"$f":"GroesseCM_1","v":170},"Gewicht",{"$f":"KG_1","v":75},"KOF",{"$f":"KG_8^0.425*GroesseCM_8^0.725/139.315","v":1.8619954939793939},"Infusionsarm",{"$f":"PatientInfusionsarm","v":"rechts"},"Pat-ID",{"$f":"IF(PatientID=\"\",\"\",PatientID)","v":1}]
[null,null,"Serum-Kreatinin",{"$f":"SerumKreatinin_1","v":0.8},"Datum",{"$f":"SerumKreatininDatum_1","v":"2021-09-06"},{"$f":"\"GFR \" & shortGFR(sGFR)","v":"GFR NM"},{"$f":"fGFR(F4,D4,PatientAlter,PatientGeschlecht,D5)","v":94.329553850453848},"Port",{"$f":"PatientPort","v":"rechts"},"Auftragsnummer",{"$f":"IF(Auftragsnummer=\"\",\"\",Auftragsnummer)","v":1}]
[null,null,"erster Tag",{"$f":"Therapiebeginn","v":"2021-09-06"},"Anzahl Zyklen",{"$f":"EmpfZyklen","v":6},"Intervalltage",{"$f":"IntervallTage","v":21},"erster Zyklus",{"$f":"DatumErsterZyklus","v":"00:00:00"},"nächster Zyklus",{"$f":"nächsterZyklus","v":"2021-09-27"}]
[null,null,"Dateipfad",{"$f":"Dateipfad","v":"c:\\Protokolle"}]
[]
[null,null,"Therapiedatum",{"$f":"PDateOV_8","v":"2021-09-13"},"Zyklustag:",8,"Zyklus: ",{"$f":"Zyklusnummer","v":1},"Uhrzeit:","00:00:00"]
[null,"Appl. Art","Medikament, Substanz","Dosis, Einheit","normale Dosierung","% Anteil Normaldosis","Trägerlsg. Volumen",null,"Ablauf",null,"Dauer","Hdz. Arzt\nUhrzeit"]
[null,"Flüssigkeitszufuhr: Jonosteril",null,null,null,null,null,null,null,null,null,"Zugangsart: peripher venös"]
[null,"i.v.","Jonosteril",{"$f":"PMSID_19550_8_B_D*1*PMSID_19550_8_F_D","v":0},500,0,"-",null,"60 min vor Atezolizumab (d1)",null,"60 min"]
[]
[null,"i.v.","Jonosteril",{"$f":"PMSID_19551_8_B_D*1*PMSID_19551_8_F_D","v":500},500,1,"-",null,"60 min vor Nab-Paclitaxel (d8,15)",null,"60 min"]
[]
[null,"Antiemese: Emetogenität hoch (CRBP), FOSAP, PALO i.v., ohne DEXA i.v.",null,null,null,null,null,null,null,null,null,"Zugangsart: peripher venös"]
[null,"i.v.","Fosaprepitant",{"$f":"PMSID_19414_8_B_D*1*PMSID_19414_8_F_D","v":0},150,0,"NaCl 0,9%, 150 ml",null,"30 min vor Atezolizumab (d1)",null,"20 min"]
[]
[null,"i.v.","Palonosetron",{"$f":"PMSID_21866_8_B_D*PMSID_21866_8_F_D","v":0},250,0,"NaCl 0,9%, 50 ml",null,"30 min vor Atezolizumab (d1)",null,"5 min"]
[]
[null,"i.v.","Granisetron",{"$f":"PMSID_19416_8_B_D*1*PMSID_19416_8_F_D","v":1},1,1,"NaCl 0,9%, 50 ml",null,"15 min vor Nab-Paclitaxel (d8,15)",null,"5 min"]
[]
[null,"Medikamentöse Tumortherapie: ATEZ1200/CRBP6/NPAC100",null,null,null,null,null,null,null,null,null,"Zugangsart: peripher venös"]
[null,"i.v.","Atezolizumab",{"$f":"PMSID_19410_8_B_D*1*PMSID_19410_8_F_D","v":0},1200,0,"NaCl 0,9%, 250 ml",null,"Reihenfolge",null,"60 min"]
[]
[null,"i.v.","Carboplatin",{"$f":"( 25 + fGFR(KG_8, GroesseCM, PatientAlter, PatientGeschlecht, SerumKreatinin_8) )* PMSID_19411_8_B_D*PMSID_19411_8_F_D","v":0},6,0,"Glucose 5%, 250 ml",null,"Reihenfolge",null,"30 min"]
[]
[null,"i.v.","Nab-Paclitaxel",{"$f":"PMSID_19412_8_B_D*KOF_8*PMSID_19412_8_F_D","v":186.19954939793939},100,1,"-",null,"Reihenfolge",null,"30 min"]
[]
[null,"Sonstige Therapie: ",null,null,null,null,null,null,null,null,null,"Zugangsart: Keine Angabe"]
[null,"p.o.",null,{"$f":"PMSID_1_8_B_D*PMSID_1_8_F_D","v":0},0,0,"-",null,"",null,"0 min"]
[]
[null,"p.o.",null,{"$f":"PMSID_2_8_B_D*PMSID_2_8_F_D","v":0},0,0,"-",null,"",null,"0 min"]
[]
[null,"p.o.",null,{"$f":"PMSID_3_8_B_D*PMSID_3_8_F_D","v":0},0,0,"-",null,"",null,"0 min"]
[]
[null,"p.o.",null,{"$f":"PMSID_4_8_B_D*PMSID_4_8_F_D","v":0},0,0,"-",null,"",null,"0 min"]

{"sheet":"Tag 15","index":4,"n_rows":37,"n_cols":12,"rows_kept":37,"cut":false,"hidden":false,"merged":[[35,6,35,7],[35,8,35,9],[36,6,36,7],[36,8,36,9],[37,6,37,7],[37,8,37,9],[32,6,32,7],[32,8,32,9],[33,6,33,7],[33,8,33,9],[34,6,34,7],[34,8,34,9],[28,6,28,7],[28,8,28,9],[30,6,30,7],[30,8,30,9],[31,6,31,7],[31,8,31,9],[25,6,25,7],[25,8,25,9],[26,6,26,7],[26,8,26,9],[27,6,27,7],[27,8,27,9],[21,6,21,7],[21,8,21,9],[23,6,23,7],[23,8,23,9],[24,6,24,7],[24,8,24,9],[18,6,18,7],[18,8,18,9],[19,6,19,7],[19,8,19,9],[20,6,20,7],[20,8,20,9],[14,6,14,7],[14,8,14,9],[16,6,16,7],[16,8,16,9],[17,6,17,7],[17,8,17,9],[11,6,11,7],[11,8,11,9],[12,6,12,7],[12,8,12,9],[13,6,13,7],[13,8,13,9],[0,0,7,0],[0,1,0,9],[1,1,1,5],[2,3,2,5],[9,6,9,7],[9,8,9,9]]}
["Entwurf",{"$f":"Protokollname","v":"Atezolizumab 1200 / Carboplatin 6 / Nab-Paclitaxel 100, nichtkleinzelliges Lungenkarzinom (PID=1238 V1.1)"},null,null,null,null,null,null,null,null,null,{"$f":"\"Z\" & Zyklusnummer & \"/d\" & F9","v":"Z1/d15"}]
[null,{"$f":"IF(PatientName=\"\",\"\",PatientName)","v":"Doe, John"},null,null,null,null,"geb.:",{"$f":"PatientGeboren","v":"1950-01-01"},"Alter",{"$f":"DATEDIF(PatientGeboren,NOW(),\"y\")&\"J \"&MOD(DATEDIF(PatientGeboren,NOW(),\"m\"),12)&\"M\"","v":"71J 8M"},"Geschlecht",{"$f":"PatientGeschlecht","v":"m"}]
[null,null,"Diagnose",{"$f":"IF(Diagnose=\"\",\"-\",Diagnose)","v":"Nichtkleinzelliges Lungenkarzinom"},null,null,"Stadium",{"$f":"IF(Stadium=\"\",\"\",Stadium)","v":"IV"},"Therapiemodus",{"$f":"IF(Therapiemodus<>\"\",Therapiemodus,\"\")","v":"Erstlinie"},"Erstdiagnose",{"$f":"IF(ErstdiagnoseDatum,ErstdiagnoseDatum,\"\")","v":"2021-09-06"}]
[null,null,"Größe",{"$f":"GroesseCM_8","v":170},"Gewicht",{"$f":"KG_8","v":75},"KOF",{"$f":"KG_15^0.425*GroesseCM_15^0.725/139.315","v":1.8619954939793939},"Infusionsarm",{"$f":"PatientInfusionsarm","v":"rechts"},"Pat-ID",{"$f":"IF(PatientID=\"\",\"\",PatientID)","v":1}]
[null,null,"Serum-Kreatinin",{"$f":"SerumKreatinin_8","v":0.8},"Datum",{"$f":"SerumKreatininDatum_8","v":"2021-09-06"},{"$f":"\"GFR \" & shortGFR(sGFR)","v":"GFR NM"},{"$f":"fGFR(F4,D4,PatientAlter,PatientGeschlecht,D5)","v":94.329553850453848},"Port",{"$f":"PatientPort","v":"rechts"},"Auftragsnummer",{"$f":"IF(Auftragsnummer=\"\",\"\",Auftragsnummer)","v":1}]
[null,null,"erster Tag",{"$f":"Therapiebeginn","v":"2021-09-06"},"Anzahl Zyklen",{"$f":"EmpfZyklen","v":6},"Intervalltage",{"$f":"IntervallTage","v":21},"erster Zyklus",{"$f":"DatumErsterZyklus","v":"00:00:00"},"nächster Zyklus",{"$f":"nächsterZyklus","v":"2021-09-27"}]
[null,null,"Dateipfad",{"$f":"Dateipfad","v":"c:\\Protokolle"}]
[]
[null,null,"Therapiedatum",{"$f":"PDateOV_15","v":"2021-09-20"},"Zyklustag:",15,"Zyklus: ",{"$f":"Zyklusnummer","v":1},"Uhrzeit:","00:00:00"]
[null,"Appl. Art","Medikament, Substanz","Dosis, Einheit","normale Dosierung","% Anteil Normaldosis","Trägerlsg. Volumen",null,"Ablauf",null,"Dauer","Hdz. Arzt\nUhrzeit"]
[null,"Flüssigkeitszufuhr: Jonosteril",null,null,null,null,null,null,null,null,null,"Zugangsart: peripher venös"]
[null,"i.v.","Jonosteril",{"$f":"PMSID_19550_15_B_D*1*PMSID_19550_15_F_D","v":0},500,0,"-",null,"60 min vor Atezolizumab (d1)",null,"60 min"]
[]
[null,"i.v.","Jonosteril",{"$f":"PMSID_19551_15_B_D*1*PMSID_19551_15_F_D","v":500},500,1,"-",null,"60 min vor Nab-Paclitaxel (d8,15)",null,"60 min"]
[]
[null,"Antiemese: Emetogenität hoch (CRBP), FOSAP, PALO i.v., ohne DEXA i.v.",null,null,null,null,null,null,null,null,null,"Zugangsart: peripher venös"]
[null,"i.v.","Fosaprepitant",{"$f":"PMSID_19414_15_B_D*1*PMSID_19414_15_F_D","v":0},150,0,"NaCl 0,9%, 150 ml",null,"30 min vor Atezolizumab (d1)",null,"20 min"]
[]
[null,"i.v.","Palonosetron",{"$f":"PMSID_21866_15_B_D*PMSID_21866_15_F_D","v":0},250,0,"NaCl 0,9%, 50 ml",null,"30 min vor Atezolizumab (d1)",null,"5 min"]
[]
[null,"i.v.","Granisetron",{"$f":"PMSID_19416_15_B_D*1*PMSID_19416_15_F_D","v":1},1,1,"NaCl 0,9%, 50 ml",null,"15 min vor Nab-Paclitaxel (d8,15)",null,"5 min"]
[]
[null,"Medikamentöse Tumortherapie: ATEZ1200/CRBP6/NPAC100",null,null,null,null,null,null,null,null,null,"Zugangsart: peripher venös"]
[null,"i.v.","Atezolizumab",{"$f":"PMSID_19410_15_B_D*1*PMSID_19410_15_F_D","v":0},1200,0,"NaCl 0,9%, 250 ml",null,"Reihenfolge",null,"60 min"]
[]
[null,"i.v.","Carboplatin",{"$f":"( 25 + fGFR(KG_15, GroesseCM, PatientAlter, PatientGeschlecht, SerumKreatinin_15) )* PMSID_19411_15_B_D*PMSID_19411_15_F_D","v":0},6,0,"Glucose 5%, 250 ml",null,"Reihenfolge",null,"30 min"]
[]
[null,"i.v.","Nab-Paclitaxel",{"$f":"PMSID_19412_15_B_D*KOF_15*PMSID_19412_15_F_D","v":186.19954939793939},100,1,"-",null,"Reihenfolge",null,"30 min"]
[]
[null,"Sonstige Therapie: ",null,null,null,null,null,null,null,null,null,"Zugangsart: Keine Angabe"]
[null,"p.o.",null,{"$f":"PMSID_1_15_B_D*PMSID_1_15_F_D","v":0},0,0,"-",null,"",null,"0 min"]
[]
[null,"p.o.",null,{"$f":"PMSID_2_15_B_D*PMSID_2_15_F_D","v":0},0,0,"-",null,"",null,"0 min"]
[]
[null,"p.o.",null,{"$f":"PMSID_3_15_B_D*PMSID_3_15_F_D","v":0},0,0,"-",null,"",null,"0 min"]
[]
[null,"p.o.",null,{"$f":"PMSID_4_15_B_D*PMSID_4_15_F_D","v":0},0,0,"-",null,"",null,"0 min"]