Search Back New search Go to resultsDiseaseMain groupCross-Sectional, Transplantation, Cellular TherapyHematologic NeoplasmsProtocol groupAcute LeukemiasAggressive LymphomasCellular TherapyHodgkin LymphomaIndolent LymphomasradiotherapyTransplantationDiseaseAcute Lymphoblastic LeukaemiaCAR T-Cell TherapyChronic Lymphocytic Leukemia / Small Lymphocytic LymphomaHodgkin LymphomaMantle Cell LymphomaNHL, B-Cell Type, Burkitt's LymphomaNHL, B-Cell Type, Diffuse Large CellNHL, B-Cell Type, Follicular Grade I-IIIaNHL, B-Cell Type, Follicular grade IIIbNHL, B-Cell Type, IndolentNHL, B-Cell Type, Lymphoplasmocytic / Waldenström's diseaseNHL, B-Cell Type, Marginal Zone LymphomaNHL, T-Cell Type, Peripheral, UnspecifiedSubgroupunfitICD10C81.-C82.-C82.7C82.9C83.0C83.1C83.3C83.7C84.4C88.0-C91.0-C91.1-MeSHLeukemia, Lymphocytic, Chronic, B-CellLymphoma, B-Cell, Marginal ZoneLymphoma, FollicularLymphoma, Large B-Cell, DiffuseLymphoma, Mantle-CellLymphoma, T-Cell, PeripheralPrecursor B-Cell Lymphoblastic Leukemia-LymphomaWaldenstrom MacroglobulinemiaSequenceCELESTIMO: MOSU(1/2/30), foll. Lymphoma °I-IIIa, C1 (PID2075) -|- MOSU30/LENA20, foll. Lymphoma °I-IIIa, C2-12 (PID2076)CELESTIMO: RITU375/LENA20, foll. Lymphoma °I-IIIa, C1 (PID2077) -|- C2 (PID2079) -|- C3 (PID2078) -|- C4 (PID2079) -|- C5(PID2078) -|- C6 (PID2079) -|- C7 (PID2078) -|- C8 (PID2079) -|- C9(PID2078) -|- C10 (PID2079) -|- C11 (PID2078) -|- C12 (PID2079)GADOLIN: OBIN1000/BEND90, foll. Lymphoma °I-IIIa, C1 (PID710) -|- C2-6 (PID724) -|- maint. (PID725)GALEN: OBIN1000/LENA20, foll. Lymphoma °I-IIIa, C1 (PID2336) -|- C2-6 (PID2337) -|- C7-12 (PID2338) -|- C13-18 (PID2339)IXAZ4/RITU1400/DEXA20, Waldenström (PID2025) -|- (PID2026) -|- (PID2027) -|- (PID310)MOSU(1/2/60), B-NHL, C1 (PID2105) -|- C2 (PID2106) -|- C3+ (PID2107)OBIN-CHOP (OBIN1000/CYCL750/DOXO50/VNCR2/PRED100), foll. Lymphoma °I-IIIa, C1 (PID1171) -|- C2-6 (PID1172) -|- C7-8 (PID1174) -|- maint. (PID1173)OBIN-CVP (OBIN1000/CYCL750/VNCR2/PRED100), foll. Lymphoma °I-IIIa, C1 (PID2416) -|- C2-6 (PID2417) -|- C7-8 (PID2418) -|- maint. (PID2419)OBIN1000/BEND90, foll. Lymphoma °I-IIIa, C1, first line (PID1645) -|- C2-6 (PID1646) -|- maint. (PID1647)OFAT-CHOP (OFAT300/CYCL750/DOXO50/VNCR2/PRED100), foll. Lymphoma °I-IIIa C1 (PID133) -|- C2-6 (PID149)RITU375 Ind., foll. Lymphoma °I-IIIa A (PID300) -|- maint. B (PID301)RITU375/CHLO6, foll. Lymphoma °I-IIIa, C1 (PID1835) -|- C2-5 (PID1836)RITU375/LENA20, foll. Lymphoma °I-IIIa, C1 (PID1529) -|- C2-6 (PID1530) -|- C7-12 (PID1531) -|- maint. (PID295)RITU375/LENA20, ind. B-NHL ind. (PID309) -|- LENA20 maint. (PID329)ChemotherapyChemo-substanceBendamustineBortezomibCarboplatinCarmustineChlorambucilCyclophosphamideCytarabineDexamethasoneDoxorubicinEtoposideFludarabineIbrutinibIdelalisibLenalidomideMelphalanMitoxantroneMosunetuzumabObinutuzumabOfatumumabPrednisoloneRituximabVincristineChemo-substanceBendamustineBortezomibCarboplatinCarmustineChlorambucilCyclophosphamideCytarabineDexamethasoneDoxorubicinEtoposideFludarabineIbrutinibIdelalisibLenalidomideMelphalanMitoxantroneMosunetuzumabObinutuzumabOfatumumabPrednisoloneRituximabVincristineChemo-substanceBendamustineBortezomibCarboplatinCarmustineChlorambucilCyclophosphamideCytarabineDexamethasoneDoxorubicinEtoposideFludarabineIbrutinibIdelalisibLenalidomideMelphalanMitoxantroneMosunetuzumabObinutuzumabOfatumumabPrednisoloneRituximabVincristineChemo-substanceBendamustineBortezomibCarboplatinCarmustineChlorambucilCyclophosphamideCytarabineDexamethasoneDoxorubicinEtoposideFludarabineIbrutinibIdelalisibLenalidomideMelphalanMitoxantroneMosunetuzumabObinutuzumabOfatumumabPrednisoloneRituximabVincristineNo. Substances123456 RadiotherapySupportive therapySupportive substanceAcetylsalicylic acidAciclovirAllopurinolAmphotericin BBalanced Crystalloid SolutionCotrimoxazoleDalteparinDexamethasoneDimetindenFosaprepitantGranisetronMesnaPantoprazoleParacetamolPegfilgrastimPrednisoloneSupportive substanceAcetylsalicylic acidAciclovirAllopurinolAmphotericin BBalanced Crystalloid SolutionCotrimoxazoleDalteparinDexamethasoneDimetindenFosaprepitantGranisetronMesnaPantoprazoleParacetamolPegfilgrastimPrednisoloneSupportive substanceAcetylsalicylic acidAciclovirAllopurinolAmphotericin BBalanced Crystalloid SolutionCotrimoxazoleDalteparinDexamethasoneDimetindenFosaprepitantGranisetronMesnaPantoprazoleParacetamolPegfilgrastimPrednisoloneSupportive substanceAcetylsalicylic acidAciclovirAllopurinolAmphotericin BBalanced Crystalloid SolutionCotrimoxazoleDalteparinDexamethasoneDimetindenFosaprepitantGranisetronMesnaPantoprazoleParacetamolPegfilgrastimPrednisoloneNo. Substances23456789Protocol classificationTherapy classificationalternativecurrent standardindividual (author)Study protocol, currentIntensityStandard doseTherapy indicationFirst lineRelapse therapySecond lineseveral possibleTherapy phaseConsolidationInductionMaintenanceSalvageTherapy intentionconsolidationcurativecurative or palliativedisease controlpalliativeRisksAlopeciaAnemia Hb below 8g/dlAstheniaAtrial FibrillationCardiotoxicityCytokine Release SyndromeDiarrheaDyspneaEdemaEmetogenicityEmetogenicity (ASCO)Emetogenicity (MASCC/ESMO)FatigueFebrile NeutropeniaGastrointestinal ToxicityHeadacheHepatotoxicityHyperglycemiaHypertensionHypokalemiaHyponatremiaHypophosphatemiaHypotensionIncrease AminotransferasesInfectionsInfusion ReactionLeukopeniaLymphopeniaMucositisNeuropathyNeurotoxicityNeutropeniaPneumoniaPruritusPyrexiaRashSepsisThrombocytopenia below 50 000/µlTumor Lysis SyndromeUpper Respiratory Tract Infection only studiesPublicationAuthorArdeshna KMBaiocchi RABudde LECzuczman MSDavies AForstpointnerGhielmini MGopal AKHeidemann WHerold MHerold M HiddemannKirschey SKönig LLiu E MacManus MMarcus RMartinelli GMorschhauser FMorschhauser F Purev ERobinson KSRummel MJSalles GScholz CWSehn LSehn LHTessoulin BTuscano JMvan Oers MHJWitzig TEDiseaseB-NHL, rezidiviert oder therapierefraktär, CD19- positiv, Lymphodepletion vor CAR T-Zell TherapieB-Non-Hodgkin-Lymphom/Hodgkin LymphomCD20-positives follikuläres Lymphom Grad I-IIIa, rezidiviert oder therapierefraktär, nach mindestens 1 rituximabhaltiger Therapie, ECOG 0-2CD20-positives indolentes B-Non-Hodgkin-Lymphom, rezidiviert oder therapierefraktär, nach mindestens 1 rituximabhaltiger Therapie, ECOG 0-2Foll. L. °I-II, Marginalzonen-L., kleines lymphozyt. L., ECOG 0-2, mind. eine Vortherapiefoll. L. °I-II, Marginalzonen-L., kleines lymphozyt. Lymphom, mind. eine Vortherapie, ECOG 0-2Foll. L. °I-IIIa, kleines lymphozyt. L., Marginalzonenl., lymphoplasmoyt. L., Drittlinie bei Rituximab- u Alkylanz-RefraktäritätFoll. Lymphom, Grad 1-2, Stadium III oder IV mit Therapieindikation, ErstbehandlungFoll. Lymphom, Grad I-III, ECOG 0-2, Erst- und ZweitlinieFoll. Lymphom, Grad I-III, Stadium III oder IV mit Therapieindikation, ECOG 0-2, ErstlinieFoll. Lymphom, Grad I-III, Stadium III und IV, Zweit- bis Drittlinie, ECOG 0-2Foll. Lymphom, Grad I-IIIa, ECOG 0-2, nach Ansprechen auf R-CHOP, R-CVP oder R-FCMFoll. Lymphom, Grad I-IIIa, Stadium I-II, ErstlinientherapieFoll. Lymphom, Grad I-IIIa, Stadium II bis IV mit Therapieindikation, Patienten älter als 50, ErstlinieFoll. Lymphom, Stadium I-IIFoll. Lymphom Grad 1-2, MCL, lymphoplasmozytisches Lymphom, Therapieindikation, Erstlinie ECOG 0-2Foll. Lymphom Grad 1-2, Stadium III und IV, ECOG 0-2, nach Ansprechen auf ErstlinieFoll. Lymphom Grad 1-3a, CD20 pos.,behandlungsbedürftig nach GELF Kriterien, ErstlinientherapieFoll. Lymphom Grad 1-3a, CD20 pos., behandlungsbedürftig nach GELF Kriterien, mind. 1 VortherapieFoll. Lymphom Grad I-III, Progress innerhalb von 6 Monaten oder nach Nichtansprechen auf Rituximab-InduktionFoll. Lymphom °I-III, Std. III u IV oder bulky Std. II, ECOG 0-2, ErstlinieFollikuläres Lymphom, ErstlinieFollikuläres Lymphom, Grad I-III, ECOG 0-2, Erst- und ZweitlinieFollikuläres Lymphom, kleines lymphozytische Lymphom, Erst- bis Fünftlinie, Karnofsky-Index größer 60%Follikuläres Lymphom °I-II, Rituximab-refraktär, ECOG 0-2Follikuläres Lymphom °I-IIIa, nicht vortherapiert, Ann-Arbor Stadium III-IV , oder II mit Bulk über 7 cm, ECOG 0-2Follikuläres Lymphom °I-IIIa, Rezidiviert oder therapierefraktär nach mindestens 2 Vortherapien, inkl. Therapie mit einem Anti-CD20-Antikörperfortgeschrittenes follikuläres Lymphom °I-IIIa, Stadium III oder IV, Erstlinie, ECOG 0-2MCL, follikuläres (Grad 1und 2), lymphoplasmozytisches, Marginalzonen-, kleines lymphozytisches Lymphom, Std. III u IV, ErstlinieMCL, follikuläres, lymphoplasmozytisches, kleines lymphozytisches u Marginalzonen-Lymphom, 2.-4.-LinieMCL, follikuläres Lymphom, Grad 1 und 2, Zweitlinie oder höherMCL, follikuläres Lymphom, lymphoplasmozytisches Lymphom, ZweitlinieNon-Hodgkin-Lymphom / Hodgkin LymphomNon-Hodgkin Lymphom, low-grade, nicht-aggressiv, Stadium III-IVrezidivierte aggressive B-NHL, 18-65 Jahre, ECOG 0-2rezidiviertes oder refraktäres B-NHL, mindestens zwei vorherige systemische BehandlungenRituximab refraktäre indolente B-NHL, ECOG 0-2OriginAbteilung für Hämatologie, Onkologie und Tumor Immunologie, Charité Berlin, DeutschlandAddenbrooke's Hospital, Cambridge, EnglandBritish Columbia Cancer Agency and the University of British Columbia, Vancouver, Canada, GADOLIN trialBritish National Lymphoma Investigation, CRC and UCL Cancer Trials Centre, London, UKCancer Research UK Centre, University of Southampton, UK, SABRINA StudieCELESTIMO trialCentre for Lymphoid Cancer, British Columbia Cancer Agency and the University of British Columbia, Vancouver, British Columbia, GAUSS StudyCentre Hospitalier Unciversitaire, Lille, FrankreichCity of Hope National Medical Center, Duarte, CADepartment of Haematology, Oncology and Pneumology, University Medical School of the Johannes Gutenberg University MainzDepartment of Medicine, Division of Medical Oncology, University of Washington School of Medicine, USADepartment of Radiation Oncology, University of Heidelberg, Heidelberg, GermanyDepartments of Medicine and Immunology, Roswell Park Cancer Institute, Buffallo, USADivision of Clinical Hemato-oncology, European Institute of Oncology, Milan, ItalyDivision of Clinical Hemato-Oncology, European Institute of Oncology, Milan, ItalyEast German Study GroupEORTC, HOVON, NCIC, CTG, BNLI, ALLG, NLGGerman Low-Grade Lymphoma Study GroupHelios Klinikum, Hämatologie/Onkologie, Erfurt, Deutschland, Studie OSHO# 19Hospices Civils de Lyon, Université Claude Bernard, Frankreich. PRIMA StudieInstitute of Oncology, Bellinzona, SchweizKings College Hospital, Denmark Hill, London, UK, GALLIUM trialMayo Clinic, Rochester, USANantes Medical University, Nantes, FranceOhio State University, Columbus, Ohio, USAPeter MacCallum Cancer Centre, Melbourne, Australia, TROG 99.03QE II Helath Sciences Centre, Halifax, Nova Scotia, CanadaRoswell Park Cancer Institute, Buffallo, NY, USARoswell Park Cancer Institute, Buffalo, NY, USAStudy Group indolent Lymphomas (StiL)The University of Washington, USA, DAWN studyUC Davis Cancer Center, Sacramento, USAUniversite Lille, Centre Hospitalier Universitaire, Lille, France, RELEVANCE trialUniversite Lille, Groupe de Recherche sur les formes Injectables et les Technologies Associees, Lille, France, GALEN trialUniversity Hospital, Ludwig Maximilian University Munich, GALLIUM trialUniversity of Texas M.D. Anderson Cancer Center, HoustonUniversité Lille, Centre Hospitalier Universitaire, Lille, France, RELEVANCE trialProtocols in Revision 65 protocols foundProtocols under revision.Chlorambucil 10, B-Non-Hodgkin Lymphoma (PID2334)DHAC - Carboplatin 5 / Cytarabine 2000 / Dexamethasone 40, Non-Hodgkin Lymphoma / Hodgkin Lymphoma. (PID2346)Fludarabine 30 / Cyclophosphamide 300, B-non-Hodgkin Lymphoma, Lymphodepletion (PID2471)Ibrutinib 560, follicular lymphoma °I-IIIa (PID2335)Idelalisib 150, indolent B-non-Hodgkin Lymphoma (PID308)Mosunetuzumab (1/2/60), B-Non-Hodgkin Lymphoma, cycle 1 (PID2105)Mosunetuzumab 30, B-Non-Hodgkin Lymphoma, cycle 3+ (PID2107)Mosunetuzumab 60, B-Non-Hodgkin lymphoma, cycle 2 (PID2106)Obinutuzumab 1000 - CHOP - Obinutuzumab 1000, follicular lymphoma °I-IIIa, maintenance (PID1173)Obinutuzumab 1000 - CHOP - Obinutuzumab 1000, follicular lymphoma °I-IIIa, cycle 7-8 (PID1174)Obinutuzumab 1000 / Bendamustine 90 - Obinutuzumab 1000 Maintenance, follicular lymphoma °I-IIIa (PID725)Obinutuzumab 1000 / Bendamustine 90 - Obinutuzumab 1000 maintenance, follicular lymphoma °I-IIIa, first-line (PID1647)Obinutuzumab 1000 / Bendamustine 90, follicular lymphoma °I-IIIa, cycle 1 (PID710)Obinutuzumab 1000 / Bendamustine 90, follicular lymphoma °I-IIIa, cycle 1, first-line (PID1645)Obinutuzumab 1000 / Bendamustine 90, follicular lymphoma °I-IIIa, cycle 2-6 (PID724)Obinutuzumab 1000 / Bendamustine 90, follicular lymphoma °I-IIIa, cycle 2-6, first-line (PID1646)Obinutuzumab 1000 / Cyclophosphamide 750 / Doxorubicin 50 / Vincristine 2 / Prednisolone 100, follicular lymphoma grade I-IIIa, cycle 1 (PID1171)Obinutuzumab 1000 / Cyclophosphamide 750 / Doxorubicin 50 / Vincristine 2 / Prednisolone 100, follicular lymphoma grade I-IIIa, cycle 2-6 (PID1172)Obinutuzumab 1000 / Cyclophosphamide 750 / Vincristine 2 / Prednisolone 100, follicular lymphoma grade I-IIIa, cycle 1. (PID2416)Obinutuzumab 1000 / Cyclophosphamide 750 / Vincristine 2 / Prednisolone 100, follicular lymphoma grade I-IIIa, cycle 2-6. (PID2417)Obinutuzumab 1000 / Lenalidomide 20 - Obinutuzumab 1000 / Lenalidomide 10 maintenance, follicular Lymphoma °I-IIIa, cycle 7-12 (PID2338)Obinutuzumab 1000 / Lenalidomide 20 - Obinutuzumab 1000 maintenance, follicular Lymphoma °I-IIIa, cycle 13-18 (PID2339)Obinutuzumab 1000 / Lenalidomide 20, follicular Lymphoma °I-IIIa, cycle 1 (PID2336)Obinutuzumab 1000 / Lenalidomide 20, follicular Lymphoma °I-IIIa, cycle 2-6 (PID2337)Obinutuzumab 1000, B-non-Hodgkin Lymphoma, maintenance (PID2341)Obinutuzumab 1000, B-Non-Hodgkin Lymphoma, Induction (PID2340)Obinutuzumab 1000, follicular lymphoma °I-IIIa, maintenance (PID2419)Obinutuzumab 1000, follicular Lymphoma °I-IIIa, cycle 7-8 (PID2418)Ofatumumab (300/1000), follicular lymphoma grade I-IIIa (PID314)Ofatumumab 1000 / Cyclophosphamide 750 / Doxorubicin 50 / Vincristine 2 / Prednisolone 100, follicular lymphoma grade I-IIIa cycle 2-6 (PID149)Ofatumumab 300 / Cyclophosphamide 750 / Doxorubicin 50 / Vincristine 2 / Prednisolone 100, follicular lymphoma grade I-IIIa cycle 1 (PID133)R-BOP - Rituximab 375 / Bendamustine 60 / Vincristine 2 / Prednisolone 100, indolent B non-Hodgkin Lymphoma and Mantle Cell Lymphoma (PID297)R-CHOP - Rituximab 375 / Cyclophosphamide 750 / Doxorubicin 50 / Vincristine 2 / Prednisolone 100, follicular lymphoma grade I-IIIa (PID294)R-COP - Rituximab 375 / Cyclophosphamide 400 / Vincristine 2 / Prednisolone 100, indolent B non-Hodgkin Lymphoma and Mantle Cell Lymphoma (PID298)R-CVP - Rituximab 375 / Cyclophosphamide 1000 / Vincristine 2 / Prednisolone 50 / Radiation, follicular lymphoma grade I-IIIa (PID1575)R-CVP - Rituximab 375 / Cyclophosphamide 750 / Vincristine 2 / Prednisolone 40, follicular lymphoma grade I-IIIa (PID296)R-DexaBEAM - Rituximab 375 / Dexamethasone 8 / Carmustine 60 / Etoposide 75 / Cytarabine 100 / Melphalan 20, B-Non-Hodgkin Lymphoma (PID1006)R-DHAC - Rituximab 375 / Carboplatin 5 / Cytarabine 2000 / Dexamethasone 40, B-Non-Hodgkin's Lymphoma/Hodgkin's Lymphoma (PID2345)R-MCP - Rituximab 375 / Mitoxantrone 8 / Chlorambucil 3 / Prednisolone 25, follicular lymphoma grade I-IIIa (PID299)RITU375/FLUD25, follicular lymphoma and indolent B-NHL (PID304)Rituximab 1400, single dose subcutaneous (PID310)Rituximab 250 / 90 Yttrium-Ibritumomab Tiuxetan consolidation, follicular lymphoma grade I-IIIa (PID305)Rituximab 250 / 90 Yttrium-Ibritumomab Tiuxetan, follicular lymphoma grade I-IIIa (PID303)Rituximab 250 / 90 Yttrium-Ibritumomab Tiuxetan, follicular lymphoma grade I-IIIa, second-line (PID306)Rituximab 375 / Bendamustine 90, indolent B-non-Hodgkin Lymphoma and Mantle Cell Lymphoma, first-line (PID271)Rituximab 375 / Bendamustine 90, indolent B-non-Hodgkin Lymphoma and Mantle Cell Lymphoma, second line (PID270)Rituximab 375 / Bortezomib 1.3, Mantle Cell Lymphoma and Follicular Lymphoma (PID278)Rituximab 375 / Chlorambucil 6, follicular lymphoma °I-IIIa, cycle 1 (PID1835)Rituximab 375 / Chlorambucil 6, Follicular Lymphoma °I-IIIa, cycle 2-5 (PID1836)Rituximab 375 / Fludarabine 25 / Cyclophosphamide 200 / Mitoxantrone 8, follicular lymphoma and Mantle Cell Lymphoma (PID272)Rituximab 375 / Lenalidomide 10, follicular lymphoma grade I-IIIa, cycle 7-12 (PID1531)Rituximab 375 / lenalidomide 20 - Lenalidomide 20 maintenance, indolent B non-Hodgkin Lymphoma induction (PID329)Rituximab 375 / Lenalidomide 20, follicular lymphoma grade I-IIIa, cycle 1 (PID1529)Rituximab 375 / Lenalidomide 20, follicular lymphoma grade I-IIIa, cycle 2-6 (PID1530)Rituximab 375 / Lenalidomide 20, indolent B non-Hodgkin Lymphoma, induction (PID309)Rituximab 375 / Radiation, follicular lymphoma (PID2333)Rituximab 375 maintenance after first-line, grade I-IIIa follicular lymphoma (PID295)Rituximab 375 maintenance after Rituximab induction, follicular lymphoma grade I-IIIa part B (PID301)Rituximab 375 maintenance after second-line, grade I-IIIa follicular lymphoma (PID302)Rituximab 375 induction, follicular lymphoma grade I-IIIa part A (PID300)Study - CELESTIMO - Lenalidomide 20, Follicular Lymphoma grade I-IIIa, cycle 2,4,6,8,10,12 (PID2079)Study - CELESTIMO - Mosunetuzumab (1/2/30), Follicular Lymphoma grade I-IIIa, cycle 1 (PID2075)Study - CELESTIMO - Mosunetuzumab 30/ Lenalidomide 20, Follicular Lymphoma grade I-IIIa, cycle 2-12 (PID2076)Study - CELESTIMO - Rituximab 375 / Lenalidomide 20, Follicular Lymphoma grade I-IIIa, cycle 1 (PID2077)Study - CELESTIMO - Rituximab 375 / Lenalidomide 20, Follicular Lymphoma grade I-IIIa, cycle 3,5,7,9,11 (PID2078)
